Biomedical and catalytic opportunities of virus-like particles in nanotechnology

B Schwarz, M Uchida, T Douglas - Advances in virus research, 2017 - Elsevier
Within biology, molecules are arranged in hierarchical structures that coordinate and control
the many processes that allow for complex organisms to exist. Proteins and other functional …

Virus-like particles in vaccine development

A Roldão, MCM Mellado, LR Castilho… - Expert review of …, 2010 - Taylor & Francis
Virus-like particles (VLPs) are multiprotein structures that mimic the organization and
conformation of authentic native viruses but lack the viral genome, potentially yielding safer …

Phage-based nanomaterials for biomedical applications

R Farr, DS Choi, SW Lee - Acta biomaterialia, 2014 - Elsevier
Recent advances in nanotechnology enable us to manipulate and produce materials with
molecular level control. In the newly emerging field of bionanomedicine, it is essential to …

Virus-like particles against infectious disease and cancer: guidance for the nano-architect

RA Hills, M Howarth - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Studying VLPs gives important insights into how the immune system makes
decisions.•Spacing antigens using DNA indicates the optimal separation for B cell …

Efficient disulfide bond formation in virus-like particles

BC Bundy, JR Swartz - Journal of biotechnology, 2011 - Elsevier
Virus-like particles (VLPs) consist of a virus's outer shell but without the genome. Similar to
the virus, VLPs are monodisperse nano-capsules which have a known morphology …

How promising are HIV-1-based virus-like particles for medical applications

SA Martins, J Santos, RDM Silva, C Rosa… - Frontiers in Cellular …, 2022 - frontiersin.org
New approaches aimed at identifying patient-specific drug targets and addressing unmet
clinical needs in the framework of precision medicine are a strong motivation for researchers …

High-yield and scalable cell-free assembly of virus-like particles by dilution

MWO Liew, YP Chuan, APJ Middelberg - Biochemical engineering journal, 2012 - Elsevier
Virus-like particles (VLPs) have been developed as safe and efficacious vaccines, and are
increasingly used as carriers for foreign peptide epitopes in modular architectures. An …

[PDF][PDF] Advances and challenges in enveloped virus-like particle (VLP)-based vaccines

S Dai, H Wang, F Deng - Journal of …, 2018 - immunologyresearchjournal.com
Virus-like particles (VLPs) are highly organized particles that self-assemble from viral
structural proteins. Like parental viruses, VLPs can be either non-enveloped or enveloped …

Production and application of insect virus-based VLPs

R Gopal, A Schneemann - Virus-Derived Nanoparticles for Advanced …, 2018 - Springer
Virus-like particles (VLPs) are self-assembling platforms composed of viral structural
proteins. They are used for a variety of purposes, ranging from the study of virus assembly to …

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

MJ Rohovie, M Nagasawa… - … & translational medicine, 2017 - Wiley Online Library
Most drug therapies distribute the agents throughout the entire body, even though the drugs
are typically only needed at specific tissues. This often limits dosage and causes discomfort …