Higher order assembly of virus‐like particles (VLPs) mediated by multi‐valent protein linkers

M Uchida, B LaFrance, CC Broomell, PE Prevelige Jr… - Small, 2015 - Wiley Online Library
Two‐and three‐dimensional assembly of nanoparticles has generated significant interest
because these higher order structures could exhibit collective behaviors/properties beyond …

The art of engineering viral nanoparticles

JK Pokorski, NF Steinmetz - Molecular pharmaceutics, 2011 - ACS Publications
Viral nanotechnology is an emerging and highly interdisciplinary field in which viral
nanoparticles (VNPs) are applied in diverse areas such as electronics, energy and next …

Engineering antiviral vaccines

X Zhou, X Jiang, M Qu, GE Aninwene, V Jucaud… - ACS …, 2020 - ACS Publications
Despite the vital role of vaccines in fighting viral pathogens, effective vaccines are still
unavailable for many infectious diseases. The importance of vaccines cannot be overstated …

In vitro assembly of virus-like particles and their applications

DT Le, KM Müller - Life, 2021 - mdpi.com
Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery.
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …

Virus‐like particles as theranostic platforms

X Sun, Z Cui - Advanced Therapeutics, 2020 - Wiley Online Library
In recent years, theranostics have received enormous attention for their use in individualized
diagnosis and treatment. The ability of viral coat protein subunits to assemble hierarchically …

Virus‐based nanoparticles as platform technologies for modern vaccines

KL Lee, RM Twyman, S Fiering… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
Nanoscale engineering is revolutionizing the development of vaccines and
immunotherapies. Viruses have played a key role in this field because they can function as …

Production and applications of engineered viral capsids

J Glasgow, D Tullman-Ercek - Applied microbiology and biotechnology, 2014 - Springer
As biological agents, viruses come in an astounding range of sizes, with varied shapes and
surface morphologies. The structures of viral capsids are generally assemblies of hundreds …

Viruses, artificial viruses and virus‐based structures for biomedical applications

P van Rijn, R Schirhagl - Advanced healthcare materials, 2016 - Wiley Online Library
Nanobiomaterials such as virus particles and artificial virus particles offer tremendous
opportunities to develop new biomedical applications such as drug‐or gene‐delivery …

Next generation vaccines and vectors: Designing downstream processes for recombinant protein‐based virus‐like particles

CL Effio, J Hubbuch - Biotechnology journal, 2015 - Wiley Online Library
In recent years, the development of novel recombinant virus‐like particles (VLPs) has been
generating new perspectives for the prevention of untreated and arising infectious diseases …

Rip it, stitch it, click it: A Chemist's guide to VLP manipulation

YH Wijesundara, FC Herbert, S Kumari, T Howlett… - Virology, 2022 - Elsevier
Viruses are some of nature's most ubiquitous self-assembled molecular containers.
Evolutionary pressures have created some incredibly robust, thermally, and enzymatically …