Surface functionalization of rod-shaped viral particles for biomedical applications

AJ Vaidya, KV Solomon - ACS applied bio materials, 2022 - ACS Publications
While synthetic nanoparticles play a very important role in modern medicine, concerns
regarding toxicity, sustainability, stability, and dispersity are drawing increasing attention to …

Virus‐like particles as powerful vaccination strategy against human viruses

I Hadj Hassine, M Ben M'hadheb… - Reviews in Medical …, 2024 - Wiley Online Library
Nowadays, viruses are not only seen as causative agents of viral infectious diseases but
also as valuable research materials for various biomedical purposes, including recombinant …

Emerging trends in the development of plant virus-based nanoparticles and their biomedical applications

M Hema, GPV Vardhan, HS Savithri… - Recent developments in …, 2019 - Elsevier
Viral nanobiotechnology is an emerging and fascinating field, dealing with the use of virus-
based nanoparticles as templates and/or building blocks to display novel molecular moieties …

Different applications of virus‐like particles in biology and medicine: vaccination and delivery systems

Z Shirbaghaee, A Bolhassani - Biopolymers, 2016 - Wiley Online Library
Virus‐like particles (VLPs) mimic the whole construct of virus particles devoid of viral
genome as used in subunit vaccine design. VLPs can elicit efficient protective immunity as …

Self-assembled viral nanoparticles as targeted anticancer vehicles

Y Wu, J Li, HJ Shin - Biotechnology and Bioprocess Engineering, 2021 - Springer
Viral nanoparticles (VNPs) comprise a variety of mammalian viruses, plant viruses, and
bacteriophages, that have been adopted as building blocks and supra-molecular templates …

The viral capsid as novel nanomaterials for drug delivery

AAA Aljabali, SS Hassan, RM Pabari… - Future science …, 2021 - Taylor & Francis
Lay abstract The purpose of this review is to highlight recent scientific developments and
provide an overview of virus self-assembly and viral particle dynamics. Viruses are …

Virus-like nanoparticles as a theranostic platform for cancer

KR Kim, AS Lee, SM Kim, HR Heo… - … in Bioengineering and …, 2023 - frontiersin.org
Virus-like nanoparticles (VLPs) are natural polymer-based nanomaterials that mimic viral
structures through the hierarchical assembly of viral coat proteins, while lacking viral …

Virus like particles: fundamental concepts, biological interactions, and clinical applications

C Benjamin, O Brohlin, A Shahrivarkevishahi… - Nanoparticles for …, 2020 - Elsevier
Nanoscale materials with multiple functionalities have presented themselves as effective
therapeutic agents. Synthetic systems like silica-based nanoparticles, colloidal systems …

Assessing sequence plasticity of a virus-like nanoparticle by evolution toward a versatile scaffold for vaccines and drug delivery

Y Lu, W Chan, BY Ko, CC VanLang… - Proceedings of the …, 2015 - National Acad Sciences
Virus-like particles (VLPs) have been extensively explored as nanoparticle vehicles for
many applications in biotechnology (eg, vaccines, drug delivery, imaging agents …

Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine

AM Wen, PH Rambhia, RH French… - Journal of biological …, 2013 - Springer
Physical virology seeks to define the principles of physics underlying viral infections,
traditionally focusing on the fundamental processes governing virus assembly, maturation …