Assembly, engineering and applications of virus-based protein nanoparticles

MG Mateu - Protein-based engineered nanostructures, 2016 - Springer
Viruses and their protein capsids can be regarded as biologically evolved nanomachines
able to perform multiple, complex biological functions through coordinated mechano …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Truncated forms of viral VP2 proteins fused to EGFP assemble into fluorescent parvovirus-like particles

L Gilbert, J Toivola, O Välilehto, T Saloniemi… - Journal of …, 2006 - Springer
Fluorescence correlation spectroscopy (FCS) monitors random movements of fluorescent
molecules in solution, giving information about the number and the size of for example nano …

Plant/bacterial virus-based drug discovery, drug delivery, and therapeutics

E Sokullu, H Soleymani Abyaneh, MA Gauthier - Pharmaceutics, 2019 - mdpi.com
Viruses have recently emerged as promising nanomaterials for biotechnological
applications. One of the most important applications of viruses is phage display, which has …

Virus-like particles: a self-assembled toolbox for cancer therapy

A Shahrivarkevishahi, LM Hagge, OR Brohlin… - Materials Today …, 2022 - Elsevier
Nanoparticle-based therapeutics have been applied in a broad range of clinical and
preclinical applications from diagnosis to treatment for cancer. A wide range of synthetic and …

[PDF][PDF] Virus-like particles as drug delivery vectors

M Zdanowicz, J Chroboczek - Acta Biochimica Polonica, 2016 - bibliotekanauki.pl
Virus-like particles (VLPs) assemble spontaneously during the viral cycle or in heterologous
systems during expression of viral structural protein. Depending on the complexity of the …

Cargo-compatible encapsulation in virus-based nanoparticles

L Li, C Xu, W Zhang, F Secundo, C Li, ZP Zhang… - Nano Letters, 2019 - ACS Publications
Molecule encapsulation in virus-based nanoparticles (VNPs) is an emerging bioinspired
way to design novel functional nanostructures and devices. Here, we report a general cargo …

Virus capsid assembly across different length scales inspire the development of virus-based biomaterials

E Selivanovitch, T Douglas - Current opinion in virology, 2019 - Elsevier
Highlights•Several different viruses require the assistance of a scaffolding protein in order to
induce proper capsid assembly.•Inter-capsid interactions may drive higher order assemblies …

Viral nanoparticles and virus‐like particles: platforms for contemporary vaccine design

EM Plummer, M Manchester - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
Current vaccines that provide protection against infectious diseases have primarily relied on
attenuated or inactivated pathogens. Virus‐like particles (VLPs), comprised of capsid …

Chimeric virus-like particles made using GAG and M1 capsid proteins providing dual drug delivery and vaccination platform

VK Deo, T Kato, EY Park - Molecular pharmaceutics, 2015 - ACS Publications
Nanobiomaterials such as enveloped virus-like particles with specificity can serve a dual
function of vaccination and drug delivery system. Here, we expressed colon carcinoma cell …