The role of virus-like particles in medical biotechnology

M Comas-Garcia, M Colunga-Saucedo… - Molecular …, 2020 - ACS Publications
Virus-like particles (VLPs) are protein-based, nanoscale, self-assembling, cage
architectures, which have relevant applications in biomedicine. They can be used for the …

Engineering virus-like particles for antigen and drug delivery

BD Hill, A Zak, E Khera, F Wen - Current Protein and Peptide …, 2018 - ingentaconnect.com
Virus-like particles (VLPs) are nanoscale biological structures consisting of viral proteins
assembled in a morphology that mimic the native virion but do not contain the viral genetic …

Rational design of virus-like particles for nanomedicine

W Shan, C Wang, H Chen, L Ren - Accounts of Materials …, 2023 - ACS Publications
Conspectus With a plethora of advances in nanotechnology and biotechnology, the
development of natural particle-based drug delivery vectors is a rapidly emerging field; …

Recent progress on the versatility of virus-like particles

C Qian, X Liu, Q Xu, Z Wang, J Chen, T Li, Q Zheng… - Vaccines, 2020 - mdpi.com
Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural
proteins of a virus in the absence of genetic material. Having similar morphology to natural …

Virus-like particles: fundamentals and biomedical applications

JL Mejía-Méndez, R Vazquez-Duhalt… - International journal of …, 2022 - mdpi.com
Nanotechnology is a fast-evolving field focused on fabricating nanoscale objects for
industrial, cosmetic, and therapeutic applications. Virus-like particles (VLPs) are self …

Applications of viral nanoparticles in medicine

I Yildiz, S Shukla, NF Steinmetz - Current opinion in biotechnology, 2011 - Elsevier
Several nanoparticle platforms are currently being developed for applications in medicine,
including both synthetic materials and naturally occurring bionanomaterials such as viral …

Development of virus‐like particles for diagnostic and prophylactic biomedical applications

B Schwarz, T Douglas - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
As ordered nanoscale architectures, viruses and virus‐like particles (VLP s) remain
unsurpassed by synthetic strategies to produce uniform and symmetric nanoparticles …

The application of virus-like particles as vaccines and biological vehicles

D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

Virus-like particles for drug delivery: a review of methods and applications

B Ikwuagwu, D Tullman-Ercek - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Virus-like particles (VLPs) are versatile structuresfor drug-delivery applications.•
Mutations to VLP structural proteins can improve VLP drug delivery.•VLP–cargo loading …

Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds

J He, L Yu, X Lin, X Liu, Y Zhang, F Yang, W Deng - Viruses, 2022 - mdpi.com
Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …