Engineering virus-like particles for antigen and drug delivery

BD Hill, A Zak, E Khera, F Wen - Current Protein and Peptide …, 2018 - ingentaconnect.com
Virus-like particles (VLPs) are nanoscale biological structures consisting of viral proteins
assembled in a morphology that mimic the native virion but do not contain the viral genetic …

The role of virus-like particles in medical biotechnology

M Comas-Garcia, M Colunga-Saucedo… - Molecular …, 2020 - ACS Publications
Virus-like particles (VLPs) are protein-based, nanoscale, self-assembling, cage
architectures, which have relevant applications in biomedicine. They can be used for the …

Bioengineering virus‐like particles as vaccines

LHL Lua, NK Connors, F Sainsbury… - Biotechnology and …, 2014 - Wiley Online Library
Virus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …

[PDF][PDF] Virus like particles as immunogens and universal nanocarriers

A Naskalska, K Pyrć - 2015 - ruj.uj.edu.pl
Over the last two decades virus‑like particles (VLPs) have become an important tool in
biomedical research and medicine. VLPs are multi‑protein structures that resemble viable …

Recent progress on the versatility of virus-like particles

C Qian, X Liu, Q Xu, Z Wang, J Chen, T Li, Q Zheng… - Vaccines, 2020 - mdpi.com
Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural
proteins of a virus in the absence of genetic material. Having similar morphology to natural …

Virus-like particles for drug delivery: a review of methods and applications

B Ikwuagwu, D Tullman-Ercek - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Virus-like particles (VLPs) are versatile structuresfor drug-delivery applications.•
Mutations to VLP structural proteins can improve VLP drug delivery.•VLP–cargo loading …

Rational design of virus-like particles for nanomedicine

W Shan, C Wang, H Chen, L Ren - Accounts of Materials …, 2023 - ACS Publications
Conspectus With a plethora of advances in nanotechnology and biotechnology, the
development of natural particle-based drug delivery vectors is a rapidly emerging field; …

Virus-like particles as antiviral vaccine: mechanism, design, and application

L Zhang, W Xu, X Ma, XJ Sun, JB Fan… - Biotechnology and …, 2023 - Springer
Virus-like particles (VLPs) are viral structural protein that are noninfectious as they do not
contain viral genetic materials. They are safe and effective immune stimulators and play …

Production of virus-like particles for vaccines

J Fuenmayor, F Gòdia, L Cervera - New biotechnology, 2017 - Elsevier
Virus-like particles (VLPs) are nanostructures that resemble the structures of viruses. They
are composed of one or more structural proteins that can be arranged in several layers and …

[PDF][PDF] Virus-like particles as drug delivery vectors

M Zdanowicz, J Chroboczek - Acta Biochimica Polonica, 2016 - bibliotekanauki.pl
Virus-like particles (VLPs) assemble spontaneously during the viral cycle or in heterologous
systems during expression of viral structural protein. Depending on the complexity of the …