The role of toll‐like receptor 4 in infectious and noninfectious inflammation
M Molteni, S Gemma, C Rossetti - Mediators of inflammation, 2016 - Wiley Online Library
Toll‐like receptor 4 (TLR4) belongs to the family of pattern recognition receptors (PRRs).
They are highly conserved receptors that recognize conserved pathogen‐associated …
They are highly conserved receptors that recognize conserved pathogen‐associated …
The role of TLR2 in infection and immunity
L Oliveira-Nascimento, P Massari… - Frontiers in …, 2012 - frontiersin.org
Toll-like receptors (TLRs) are recognition molecules for multiple pathogens, including
bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which …
bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which …
A comparative review of toll-like receptor 4 expression and functionality in different animal species
C Vaure, Y Liu - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …
component of the innate immune system. TLRs detect invading pathogens and initiate an …
Sensing of viral infection and activation of innate immunity by toll-like receptor 3
E Vercammen, J Staal, R Beyaert - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Toll-like receptors (TLRs) form a major group of transmembrane receptors that are involved
in the detection of invading pathogens. Double-stranded RNA is a marker for viral infection …
in the detection of invading pathogens. Double-stranded RNA is a marker for viral infection …
LPS/TLR4 signal transduction pathway
The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the
release of critical proinflammatory cytokines that are necessary to activate potent immune …
release of critical proinflammatory cytokines that are necessary to activate potent immune …
Toll-like receptor 4: a promising crossroads in the diagnosis and treatment of several pathologies
MM Garcia, C Goicoechea, M Molina-Álvarez… - European Journal of …, 2020 - Elsevier
Abstract Toll-like receptor 4 (TLR4) is expressed in a wide variety of cells and is the central
component of the mammalian innate immune system. Since its discovery in 1997, TLR4 has …
component of the mammalian innate immune system. Since its discovery in 1997, TLR4 has …
Soluble forms of Toll-like receptor (TLR) 2 capable of modulating TLR2 signaling are present in human plasma and breast milk
E LeBouder, JE Rey-Nores, NK Rushmere… - The Journal of …, 2003 - journals.aai.org
Dysregulation of the initial, innate immune response to bacterial infection may lead to septic
shock and death. Toll-like receptors (TLRs) play a crucial role in this innate immune …
shock and death. Toll-like receptors (TLRs) play a crucial role in this innate immune …
Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways
Inflammation is set off when innate immune cells detect infection or tissue injury. Tight
control of the severity, duration, and location of inflammation is an absolute requirement for …
control of the severity, duration, and location of inflammation is an absolute requirement for …
TLR signaling pathway in patients with sepsis
The pathogenesis of sepsis involves complex interaction between the host and the infecting
microorganism. Bacterial recognition and signaling are essential functions of the cells of …
microorganism. Bacterial recognition and signaling are essential functions of the cells of …
The role of Toll-like receptor 2 in microbial disease and immunity
LM Wetzler - Vaccine, 2003 - Elsevier
Cells expressing Toll-like receptor (TLR), TLR2 in association with TLR1, TLR6 or some
other unknown co-receptor can respond upon interaction with a large variety of microbial …
other unknown co-receptor can respond upon interaction with a large variety of microbial …