Brain activation induced by chronic psychosocial stress in mice

MA Laine, E Sokolowska, M Dudek, SA Callan… - Scientific reports, 2017 - nature.com
Chronic psychosocial stress is a well-established risk factor for neuropsychiatric diseases.
Abnormalities in brain activity have been demonstrated in patients with stress-related …

Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress

S Kumar, R Hultman, D Hughes, N Michel… - Nature …, 2014 - nature.com
Psychological stress contributes to the onset and exacerbation of nearly all neuropsychiatric
disorders. Individual differences in stress-regulatory circuits can therefore dramatically affect …

Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways

F Quessy, T Bittar, LJ Blanchette, M Lévesque… - Scientific Reports, 2021 - nature.com
Our ability to develop the cognitive strategies required to deal with daily-life stress is
regulated by region-specific neuronal networks. Experimental evidence suggests that …

Social defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex

C Numa, H Nagai, M Taniguchi, M Nagai… - Scientific reports, 2019 - nature.com
We recently reported that dopamine D1 receptor in the medial prefrontal cortex (mPFC) is
activated by subthreshold social defeat stress and suppresses the induction of depressive …

Rodent models of social stress and neuronal plasticity: Relevance to depressive-like disorders

D Patel, MJ Kas, S Chattarji, B Buwalda - Behavioural brain research, 2019 - Elsevier
Exposure to severe or persistent social stress may lead to the development of psychiatric
disorders such as anxiety and depression. These mood disorders are associated with …

[HTML][HTML] Chronic stress produces enduring sex-and region-specific alterations in novel stress-induced c-Fos expression

KM Moench, MR Breach, CL Wellman - Neurobiology of stress, 2019 - Elsevier
Prolonged or repeated exposure to stress increases risk for a variety of psychological
disorders, many of which are marked by dysfunction of corticolimbic brain regions. Notably …

Stress-induced neuronal colony stimulating factor 1 provokes microglia-mediated neuronal remodeling and depressive-like behavior

ES Wohleb, R Terwilliger, CH Duman, RS Duman - Biological psychiatry, 2018 - Elsevier
Background Chronic stress exposure causes neuronal atrophy and synaptic deficits in the
medial prefrontal cortex (PFC), contributing to development of anxiety-and depressive-like …

Chronic stress-induced behaviors correlate with exacerbated acute stress-induced cingulate cortex and ventral hippocampus activation

C Fee, T Prevot, K Misquitta, M Banasr, E Sibille - Neuroscience, 2020 - Elsevier
Altered activity of corticolimbic brain regions is a hallmark of stress-related illnesses,
including mood disorders, neurodegenerative diseases, and substance abuse disorders …

Repeated social defeat selectively increases δFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex

M Hinwood, RJ Tynan, TA Day, FR Walker - Cerebral Cortex, 2011 - academic.oup.com
Exposure to social stress has been linked to the development and maintenance of mood-
related psychopathology; however, the underlying neurobiological changes remain …

Psychosocial stress reversibly disrupts prefrontal processing and attentional control

C Liston, BS McEwen, BJ Casey - Proceedings of the …, 2009 - National Acad Sciences
Relatively little is known about the long-term neurobiological sequelae of chronic stress,
which predisposes susceptible patients to neuropsychiatric conditions affecting the …