The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research

LB Rizzo, LG Costa, RB Mansur, W Swardfager… - Neuroscience & …, 2014 - Elsevier
… , neurotrophic deficiencies and telomere shortening) converge on a model of accelerated
aging (AA). Aging can be understood as a multidimensional process involving physical, …

Accelerated aging in bipolar disorder: A comprehensive review of molecular findings and their clinical implications

GR Fries, MJ Zamzow, T Andrews, O Pink… - Neuroscience & …, 2020 - Elsevier
… Finally, inflammation also seems to be a logical target in the clinical treatment of the
disorder. A 2017 meta-analysis on the use of anti-inflammatory treatments for mood disorders …

Cancer treatment as an accelerated aging process: assessment, biomarkers, and interventions

A Hurria, L Jones, HB Muss - American Society of Clinical Oncology …, 2016 - ascopubs.org
… feasible to implement in both daily clinical practice and among patients enrolled in clinical
trials. Geriatric assessment tools that can be mailed to the patient and completed prior to the …

Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care

JE Carroll, JE Bower, PA Ganz - Nature Reviews Clinical Oncology, 2022 - nature.com
… Given the mounting evidence that cancer and cancer treatments might accelerate ageing
in various ways, we consider what role behavioural factors could have in modifying these …

Impact of early personal‐history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan

DW Belsky, A Caspi, HJ Cohen, WE Kraus… - Aging cell, 2017 - Wiley Online Library
… Our principle finding is that young adults who show signs of rapid biological aging are …
Our measurement of accelerated aging is necessarily imperfect. Methods are still under …

Evidence of accelerated aging among African Americans and its implications for mortality

ME Levine, EM Crimmins - Social Science & Medicine, 2014 - Elsevier
accelerated aging compared to whites. However, these differences should decrease with
age … Finally, we hypothesize that racial differences in pace of aging will account for the higher …

Accelerated aging among cancer survivors: from pediatrics to geriatrics

TO Henderson, KK Ness, HJ Cohen - American Society of Clinical …, 2014 - ascopubs.org
… produce changes in function at the organ level that in many respects mimic those of aging (…
premature aging syndrome,” in the older adult these changes are superimposed on the age-…

Clinical implications of aging with HIV infection: perspectives and the future medical care agenda

G Guaraldi, FJ Palella Jr - Aids, 2017 - journals.lww.com
clinical care management considerations for healthcare professionals caring for HIV+ persons.
… as to whether HIV infection constitutes a state of accentuated or accelerated aging [14] . …

Of sound mind and body: depression, disease, and accelerated aging

O M. Wolkowitz, V I. Reus… - Dialogues in clinical …, 2011 - Taylor & Francis
… to the medical comorbidity burden and to accelerated aging: … neurotrophic activity, and
accelerated cell aging, manifest as … of physical disease and of accelerated aging at the cellular …

Accelerated aging and human immunodeficiency virus infection: emerging challenges of growing older in the era of successful antiretroviral therapy

R Bhatia, P Ryscavage, B Taiwo - Journal of neurovirology, 2012 - Springer
… shared by normal aging and HIV infection and explore the growing spectrum of clinical
manifestations associated with the accelerated aging phenotype in HIV-infected individuals. …