[HTML][HTML] Psychological and metabolic stress: a recipe for accelerated cellular aging?

ES Epel - Hormones, 2009 - Springer
… be conducive to several cell aging mechanisms, mainly dampening telomerase and leading
to telomere length (TL) shortening and cell senescence. Immune cell telomere shortness is …

Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study

JE Verhoeven, D Révész, ES Epel, J Lin… - Molecular …, 2014 - nature.com
… is associated with accelerated biological aging, and whether … do further impact on biological
aging. Data are from the … patients show accelerated cellular aging according to a ‘dose…

Dysregulated physiological stress systems and accelerated cellular aging

D Revesz, JE Verhoeven, Y Milaneschi… - … of aging, 2014 - Elsevier
… The found association between the highest tertile of AUCi with shorter LTL in our sample
suggests that cellular aging is especially linked to hyperactivity of the HPA-axis, and less with …

Depression gets old fast: do stress and depression accelerate cell aging?

OM Wolkowitz, ES Epel, VI Reus… - Depression and …, 2010 - Wiley Online Library
… Various explanations for “accelerated aging” in depression have been proposed, such as …
that “accelerated aging” in depression occurs at the level of the individual cell and that it can …

[HTML][HTML] Early detection of accelerated aging and cellular decline (AACD): A consensus statement

M Cesari, A Cherubini, JM Guralnik, A Beresniak… - Experimental …, 2021 - Elsevier
… The cellular hallmarks of accelerated aging and their clinical expression may be grouped …
terms ‘accelerated aging and cellular decline’ (AACD) and/or ‘age-associated cellular decline’. …

Traumatic stress and accelerated cellular aging: from epigenetics to cardiometabolic disease

EJ Wolf, FG Morrison - Current psychiatry reports, 2017 - Springer
accelerated cellular aging; and (e) the influence of chronological age on accelerated cellular
aging and whether the impact of various stressors on cellular age is dependent on critical …

Physician-training stress and accelerated cellular aging

KK Ridout, SJ Ridout, C Guille, DA Mata, H Akil… - Biological …, 2019 - Elsevier
… of residency training by longitudinally assessing telomere-length attrition across the
internship year and how this marker of cellular aging relates to factors of the training experience. …

Posttraumatic stress disorder-related cardiovascular disease and accelerated cellular aging

EJ Wolf, PP Schnurr - Psychiatric annals, 2016 - journals.healio.com
… these behavioral and biological mechanisms lead to accelerated cellular aging, as regulated
in the … the mechanisms linking PTSD to accelerated aging and to develop interventions to …

Early life adversity predicts an accelerated cellular aging phenotype through early timing of puberty

EJ Hamlat, TB Neilands, B Laraia, J Zhang… - Psychological …, 2023 - cambridge.org
… In meta-analysis, early adversity was associated with early pubertal timing as well as
accelerated cellular aging, as indexed by both epigenetic age and TL (Colich, Rosen, Williams, & …

Prevention of accelerated cell aging in the Werner syndrome

T Davis, MF Haughton, CJ Jones… - Annals of the New York …, 2006 - Wiley Online Library
… The molecular mechanism of WS appears to be related to accelerated cell aging. … cellular
senescence. This is postulated to contribute to normal human aging and is accelerated in WS, …