F Qi, F Gao, Y Cai, X Han, Y Qi, J Ni, J Sun… - Frontiers in …, 2021 - frontiersin.org
… Finally, we show that age and presence of non-blood cancers change … We then compared age-related transcriptome changes found in this study in blood with those found by …
… it to that of the peripheral blood mononuclear cell (PBMCs) of the … To assess aging-associated changes in the plasma exRNA … processes as a result of aging. Additionally, plasma RNA …
… , cellular and tissue level 12 , a transcriptome analysis might lend greater insight than a … chronological age. In contrast to the relatively invariable genome sequence, the transcriptome is …
… T cell exhaustion, we also mined the agingblood cell transcriptome for related markers [30]. … varying with bloodaging. Although CCL4L2 and DUSP4 genes increased over bloodaging, …
… of aging in humans. T cells and monocytes can be isolated from an easily accessible tissue (blood), and both have known roles in the development of age… of the agingtranscriptome, we …
MN Shokhirev, AA Johnson - Aging cell, 2021 - Wiley Online Library
… A blood-specific aging model identified genes enriched for inflammatory response, activation of the immune system, and negative regulation of cell death (Figure 5c). In the heart, …
O González-Velasco, D Papy-García… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… human brain aging: focusing on sex differences in gene expression and splicing [11]; or comparing the transcriptional landscape of brain tissue samples and blood … of transcriptome data …
R Li, J Zou, D Pei, T Pan, B Yang, X Liu… - … and Targeted Therapy, 2023 - nature.com
… Thus, we hypothesized that aging-related cellular landscape … age-related genes in human peripheral blood, we initially identified multiple gene clusters significantly correlated with age (…
… , on the effects of aging on gene expression at a transcriptome-level in the normal … The second sample consisted of 1240 individuals ranging in age from 15-94 in which fresh blood …