… isolation and partial sequencing of the meningovascular amyloid β-protein (Aβ) by George
… fundamental mechanism of Alzheimer disease (AD). Ever since Alzheimer peered through …

… Biometals play an important role in Alzheimer disease, and recent … amyloid β-peptide (Aβ)
metabolism in cell culture. Treatment of Chinese hamster ovary cells overexpressing amyloid …

… for brain amyloidosis with plasma Aβ42/Aβ40 were evaluated for an Alzheimer disease
prevention trial similar to the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) …

… to support a role for oxidative stress in Alzheimer's disease (AD), with increased levels of …
of the Amyloid β peptide (Aβ), this is the result of either an elevated generation from amyloid …

… amyloid formation of another, different protein: the amyloid cross-… Alzheimer disease
amyloid-β (Aβ) peptide and other amyloid … between different amyloid diseases. We argue that the …

The biochemistry of amyloid proteins has been a fascinating and important area of research
because of its contribution to our understanding of protein folding dynamics and assembly …

… Disease-modifying treatments for Alzheimer disease (AD) have focused mainly on reducing
levels of amyloid-β (Aβ) in the brain. Some compounds have achieved this goal, but none …

… studying Alzheimer disease has been centered on amyloid-β, such that the amyloid
cascade … Indeed, amyloid-β is, by the current definition of the disease, an obligate player in …

… Extracellular amyloid β (Aβ) that confers neurotoxicity and modulates synaptic plasticity
and memory function has been central to the amyloid hypothesis of Alzheimer's disease (AD) …

Alzheimer’s disease (AD) is characterized by the deposition of amyloid in the extracellular
compartment of the brain in the form of congophilic amyloid angiopathy (CAA) and amyloid …