… brain and blood compartments. In this review, we discuss mechanisms by which SARS-CoV-… -2 entry and infection, which could contribute to neuronal and endothelial damage and loss. …
… structural damage to the BBB elicits the SARS-CoV-2 infection to the CNS. Herein, we present the case reports of two patients with a brain … a possible BBB damage which highlights the …
L Zhang, L Zhou, L Bao, J Liu, H Zhu, Q Lv… - Signal transduction and …, 2021 - nature.com
… of SARS-CoV-2 spike protein (SARS-CoV-2-S) in the brains of … the co-localization of SARS-CoV-2-S with blood vessels in the … a clue that SARS-CoV-2 infection could damage BBB via …
O Constant, J Barthelemy, K Bollore, E Tuaillon… - Frontiers in …, 2021 - frontiersin.org
… We observed low replication of SARS-CoV-2 that was accompanied by very moderate … of brain access following SARS-CoV-2 infection does not seem to be directed by brain …
… , that SARS-COV-2 associated endothelial cell dysfunction preludes the neuropathology associated with SARS-COV-… or therapies that prevent BBB damage may be effective in treating …
S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
… in their paracellular tightness, we found SARS-CoV-2 in the … transport of virus across the blood-brainbarrier (BBB) in vitro. … the respiratory system, damage and dysfunction have also …
D Adesse, L Gladulich, L Alvarez-Rosa… - … and Barriers of the CNS, 2022 - Springer
… the impact of SARS-CoV-2 on the NVU, the expression profile of SARS-CoV-2 receptors in the … can also enter the fourth ventricle directly through a damagedblood–CSF barrier. Indeed, …
P Wang, L Jin, M Zhang, Y Wu, Z Duan, Y Guo… - Nature Biomedical …, 2023 - nature.com
… alveolus and blood–brainbarrier (BBB) tissue chips that recapitulates neuropathogenesis associated with infection by SARS-CoV-2. Direct exposure of the BBB chip to SARS-CoV-2 …