Peripheral inflammation and bloodbrain barrier disruption: effects and mechanisms

X Huang, B Hussain, J Chang - CNS neuroscience & …, 2021 - Wiley Online Library
blood circulation, the bloodbrain barrier (BBB) regulates cellular and molecular exchange
between the blood vessels and brain … , probably due to BBB disruption induced by peripheral …

Blood-brain barrier disruption in multiple sclerosis

A Minagar, JS Alexander - Multiple Sclerosis Journal, 2003 - journals.sagepub.com
… Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new
lesions in multiple sclerosis . Brain 1990; 113: 1477-1489 . … The blood brain barrier

Assessment of bloodbrain barrier disruption in stroke

A Kassner, Z Merali - Stroke, 2015 - Am Heart Assoc
… evolution of bloodbrain barrier (BBB) disruption after stroke. The extent of BBB disruption is
… The period during which there is greatest disruption of the BBB coincides with the maximum …

Development, maintenance and disruption of the blood-brain barrier

B Obermeier, R Daneman, RM Ransohoff - Nature medicine, 2013 - nature.com
The interface between the blood circulation and the neural tissue features unique characteristics
that are encompassed by the term 'blood-brain barrier' (BBB). The main functions of this …

Cellular mechanisms of IL‐17‐induced bloodbrain barrier disruption

J Huppert, D Closhen, A Croxford, R White… - The FASEB …, 2010 - Wiley Online Library
barrier disruption (Fig. 1A). Furthermore, we wanted to exclude the possibility that the
barrier-disrupting … To our surprise, IL-22 did not induce barrier disruption in bEnd.3 monolayers (…

Early bloodbrain barrier disruption in human focal brain ischemia

LL Latour, DW Kang, MA Ezzeddine… - Annals of Neurology …, 2004 - Wiley Online Library
Loss of integrity of the bloodbrain barrier (BBB) resulting from ischemia/reperfusion is
believed to be a precursor to hemorrhagic transformation (HT) and poor outcome. We used a …

Consequences of repeated blood-brain barrier disruption in football players

N Marchi, JJ Bazarian, V Puvenna, M Janigro… - PloS one, 2013 - journals.plos.org
blood-brain barrier disruption (BBBD) and the accompanying surge of the astrocytic protein
S100B in blood … We also wished to determine whether these events result in disrupted white …

Pathomechanisms of bloodbrain barrier disruption in ALS

N Kakaroubas, S Brennan, M Keon… - Neuroscience …, 2019 - Wiley Online Library
… The blood-brain barrier (BBB) and the blood-spinal cord barrier (BSCB) are responsible
for controlling the microenvironment within neural tissues in humans. These barriers are …

Clinical trial of blood-brain barrier disruption by pulsed ultrasound

A Carpentier, M Canney, A Vignot, V Reina… - Science translational …, 2016 - science.org
… , disrupting the blood-brain barrier long enough for subsequent chemotherapy to reach the
brain. … showed evidence of effectiveness to disrupt the blood-brain barrier, paving the way for …

Severe bloodbrain barrier disruption and surrounding tissue injury

B Chen, B Friedman, Q Cheng, P Tsai, E Schim… - Stroke, 2009 - Am Heart Assoc
… after severe vascular disruption. We sought to characterize severe vascular disruption with
high-… confirmation, and then compared such vascular disruption to evidence of tissue injury. …