[HTML][HTML] SARS-CoV-2 infection and persistence in the human body and brain at autopsy

SR Stein, SC Ramelli, A Grazioli, JY Chung, M Singh… - Nature, 2022 - nature.com
SARS-CoV-2 RNA in multiple anatomic sites, including throughout the brain, as late as
230 days following symptom onset in one case. Despite extensive distribution of SARS-CoV-2 …

What can cerebrospinal fluid testing and brain autopsies tell us about viral neuroinvasion of SARSCoV‐2

YC Li, Y Zhang, BH Tan - Journal of Medical Virology, 2021 - Wiley Online Library
… and brain autopsies in COVID-19 patients. SARS-CoV-2 has been detected in the CSF or
brain … Similarly, many decreased patents with COVID-19 who underwent brain autopsies were …

SARSCoV‐2 and the brain: A review of the current knowledge on neuropathology in COVID‐19

A Maiese, AC Manetti, C Bosetti, F Del Duca… - Brain …, 2021 - Wiley Online Library
… (43) studied nine brains out of 21 autopsies performed on subjects who died from COVID-19.
In one case, the death was attributed to necrotizing encephalitis, and microscopic …

What can we learn from brain autopsies in COVID-19?

SS Mukerji, IH Solomon - Neuroscience letters, 2021 - Elsevier
… in COVID-19 and whether SARS-CoV-2 has the potential for … human autopsies in fatal
COVID-19, including highlighting studies that investigate for the presence of SARS-CoV-2 in brain

The autopsy at the time of SARS-CoV-2: Protocol and lessons

L Carpenito, M D'Ercole, F Porta, E Di Blasi… - Annals of diagnostic …, 2020 - Elsevier
… patients infected with SARS-CoV-2 [22,23], it appears indispensable to perform the evisceration
and examination of the brain and brainstem, for the completeness of the autopsy and for …

[HTML][HTML] Mapping of SARS-CoV-2 brain invasion and histopathology in COVID-19 disease

GE Serrano, JE Walker, R Arce, MJ Glass, D Vargas… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… The findings of this study are generally in agreement with previously reported autopsy
examinations of the brains of COVID-19 disease subjects, in that serious complications like …

SARS-CoV-2 brain regional detection, histopathology, gene expression, and immunomodulatory changes in decedents with COVID-19

GE Serrano, JE Walker, C Tremblay… - … of Neuropathology & …, 2022 - academic.oup.com
… RT-PCR screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene
viral … Although OB is a major brain portal for SARS-CoV-2, COVID-19 brain changes are more …

[HTML][HTML] SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature

L Lebrun, L Absil, M Remmelink… - Acta neuropathologica …, 2023 - Springer
… In this study, different areas of the brain were sampled at the moment of autopsy and were
… , the presence of SARS-CoV-2 RNA in the brain was confirmed in all autopsies performed in …

Brain autopsies in fatal COVID-19 and postulated pathophysiology: more puzzling than a Rubik's cube

S Mehta, S Bhandari, S Mehta - Journal of Clinical Pathology, 2021 - jcp.bmj.com
… ruling out neuronal pathway of spread of SARS-CoV-2. Also, SARS-CoV-2 virus was not
detected in the brain, suggesting indirect effect of SARS-CoV-2 in the brain of these patients. …

[PDF][PDF] SARS-CoV-2 infection and persistence throughout the human body and brain

D Chertow, S Stein, S Ramelli, A Grazioli, JY Chung… - 2021 - academia.edu
… We categorized autopsy cases of SARS-CoV-2 infection as “early” (n=17), “mid” 115 (n=13),
or “late” (n=14) by illness day (D) at the time of death, being ≤D14, D15-D30, or ≥D31, 116 …