[HTML][HTML] The molecular landscape of premenopausal breast cancer

S Liao, RJ Hartmaier, KP McGuire, SL Puhalla… - Breast Cancer …, 2015 - Springer
… Here we set out to understand differences in molecular make-up between preM and postM
breast cancer, starting with the analysis of differential gene expression (DE). As a first step, …

[HTML][HTML] PI3K/AKT/mTOR signaling pathway in breast cancer: from molecular landscape to clinical aspects

D Miricescu, A Totan, II Stanescu-Spinu… - … journal of molecular …, 2020 - mdpi.com
Molecular Types of Breast Cancer Using gene expression profiling, breast cancer molecular
… In order to define the types of breast cancer, the expression of three tumor markers was …

[HTML][HTML] Resistance to antibody-drug conjugates targeting HER2 in breast cancer: molecular landscape and future challenges

L Guidi, G Pellizzari, P Tarantino, C Valenza… - Cancers, 2023 - mdpi.com
Simple Summary Human epidermal growth factor receptor 2 (HER2)-positive metastatic
breast cancer (mBC) represents a subgroup of breast cancer characterized by an aggressive …

[HTML][HTML] Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer

F Mosele, B Stefanovska, A Lusque, AT Dien… - Annals of …, 2020 - Elsevier
… -mutated, hormone receptor-positive (HR+)/Her2− metastatic breast cancer (mBC).
Nevertheless, it is still unclear how to integrate this new drug family in the treatment landscape. …

Therapeutic implications of the molecular and immune landscape of triple-negative breast cancer

AC Gregório, M Lacerda, P Figueiredo… - Pathology & Oncology …, 2018 - Springer
Molecular heterogeneity is also prominent in the triple-negative breast cancer subtype, and
… current knowledge on the molecular and immune profiles of breast cancer, and its impact on …

[HTML][HTML] The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences

JW Pan, MMA Zabidi, PS Ng, MY Meng… - Nature …, 2020 - nature.com
… patients have better survival than other racial/ethnic groups 60,61 , and the molecular
basis of breast cancers in Asian women reported in this study highlights some of the possible …

[HTML][HTML] Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer

Z Yi, G Rong, Y Guan, J Li, L Chang, H Li, B Liu… - … Breast Cancer, 2020 - nature.com
… of 1184 patients with invasive breast cancer. In addition, a single-… -negative, mutation-positive
breast cancer. Peripheral blood was … metastatic breast cancers may benefit from pyrotinib. …

[HTML][HTML] The molecular landscape of high-risk early breast cancer: comprehensive biomarker analysis of a phase III adjuvant population

TR Wilson, J Yu, X Lu, JM Spoerke, Y Xiao… - … Breast Cancer, 2016 - nature.com
Breast cancer is a heterogeneous disease and patients are … the molecular landscape of
high-risk breast cancer patients … DNA and RNA were extracted from 861 breast cancer samples …

[HTML][HTML] Molecular landscape of therapy-related myeloid neoplasms in patients previously treated for gynecologic and breast cancers

S Khalife-Hachem, K Saleh, F Pasquier… - …, 2021 - journals.lww.com
… We aimed to describe the molecular landscape of TRMN at diagnosis, among 77 patients
with previous gynecologic and breast cancer with a dedicated next-generation sequencing …

The genomic landscape of breast cancer and its interaction with host immunity

S Luen, B Virassamy, P Savas, R Salgado, S Loi - The Breast, 2016 - Elsevier
… genomic alteration landscapes and host anti-tumour immunity are being explored. This
review article aims to summarise the genomic and driver landscape of breast cancer, and …