Does SARSCov2 invade the brain? Translational lessons from animal models

S Natoli, V Oliveira, P Calabresi… - European journal of …, 2020 - Wiley Online Library
… The expression of this receptor in neurons and endothelial cells hints that SARS-CoV-2
may … in the short and medium term is therefore of great importance. In this brief review, we …

Unraveling the possible routes of SARS-COV-2 invasion into the central nervous system

M Lima, V Siokas, AM Aloizou, I Liampas… - … treatment options in …, 2020 - Springer
review, we aim to shed some light into how this novel virus can impact the central nervous
system (CNS) by describing the routes of its invasion … [59] or finally invade the CNS, via the …

Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B. 1.1. 7 emergence

…, COVID-19 Genomics UK (COG-UK) Consortium‡… - Science, 2021 - science.org
SARS-CoV-2 lineages (1, 6–9) and potentially a greater risk of hospitalization (10–13). The
spatial heterogeneity of SARS-CoV-2 … respond effectively to future SARS-CoV-2 variants. We …

SARS-CoV-2 invasion of the central nervous: a brief review

R Siddiqui, MR Mungroo, NA Khan - Hospital Practice, 2021 - Taylor & Francis
… But how does a respiratory virus invade the highly protected CNS? Here, we reviewed
available literature and case reports to determine CNS involvement in COVID-19, and to identify …

SARS-CoV-2, ACE2 expression, and systemic organ invasion

UM Ashraf, AA Abokor, JM Edwards… - Physiological …, 2021 - journals.physiology.org
… ACE2 disruption initiated through the binding of SARS-CoV-2 may have short- and long-term
pathophysiological consequences to numerous organ systems that utilize ACE2 for proper …

Neuromechanisms of SARS-CoV-2: a review

MF DosSantos, S Devalle, V Aran, D Capra… - Frontiers in …, 2020 - frontiersin.org
… However, evidence related to the presence of SARS-CoV-2 in the CNS, its direct impact on
… Here, we review the current literature that indicates that SARS-CoV-2 can invade the nervous …

[HTML][HTML] Understanding on the possible routes for SARS CoV-2 invasion via ACE2 in the host linked with multiple organs damage

N Kirtipal, S Kumar, SK Dubey, VD Dwivedi… - Infection, Genetics and …, 2022 - Elsevier
… Hence, this review summarizes the multiple organs invasion by SARS CoV-2 linked with …
helpful in the management of the COVID-19 pathogenesis under life-threatening conditions. …

Possible routes of SARSCoV2 invasion in brain: in context of neurological symptoms in COVID19 patients

A Kumar, V Pareek, P Prasoon, MA Faiq… - Journal of …, 2020 - Wiley Online Library
… In this review article, we have discussed the possible routes of SARS-CoV-2 brain entry …
We made a comprehensive review of the emerging SARS-CoV-2 specific evidence, and that for …

Neurological complications and infection mechanism of SARS-COV-2

D Wan, T Du, W Hong, L Chen, H Que, S Lu… - Signal Transduction and …, 2021 - nature.com
… Understanding the invasion mechanisms of SARS-CoV-2 in the nervous system is critical …
relevant for SARS-CoV-2. Herein, we review previously documented SARS-CoV-2-associated …

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

J Meinhardt, J Radke, C Dittmayer, J Franz… - Nature …, 2021 - nature.com
COVID-19, SARS-CoV-2 penetrance of the CNS is likely. By various means, we demonstrate
the presence of SARS-CoV-2 … individuals with COVID-19 who had relatively short disease …