… celltypes, and is disrupted in many diseases. We describe large-scale single-base resolution DNAmethylation … This revised model changes our expectations of the type of methylation …
… To discover DNAmethylationchanges that associate with gene expression changes, we propose a new method that uses the entire differential methylation profile in the vicinity of a …
… cell-type compositions. To analyze DNAmethylationvariation from different perspectives, we … reference data sets for cancer samples that included primary tumors and cancer cell lines. …
… variation in DNAmethylation profiles. Furthermore, there was an enrichment of SNPs that affect both methylation … of the methylation array provides a relatively low resolution snapshot of …
… The increased detail in describing leukocyte subtypes using the extended libraries will be crucial for controlling for aging-related DNAmethylationchanges; age-associated changes in …
… can also profile DNAmethylation at single-base resolution [40, 41]. … DNAmethylation in many celltypes or tissues to study dynamic DNAmethylationchanges across different celltypes, …
N Loyfer, J Magenheim, A Peretz, G Cann, J Bredno… - Biorxiv, 2022 - biorxiv.org
… , for identifying pathological changes in DNAmethylation, and for the interpretation of … The resolution of the atlas yields a quantitative understanding of composite tissues, and …
… allow the construction of genomic maps of DNAmethylation at single-base resolution [30]. In the … Weak DNAmethylationdifferences can be better measured by estimating the standard …
… DNAmethylation across human tissues better, we obtained post-mortem samples of 18 tissue types … Here we have presented the deepest set of base resolution maps of mCG and mCH …