Mild SARS-CoV-2 infection modifies DNA methylation of peripheral blood mononuclear cells from COVID-19 convalescents

J Huoman, S Sayyab, E Apostolou, L Karlsson… - medRxiv, 2021 - medrxiv.org
… the start of the COVID-19 pandemic, we performed differential DNA methylation analyses,
using … A linear model was fitted to the filtered, normalised and SVD-corrected DNA methylation

Adipose tissue and blood leukocytes ACE2 DNA methylation in obesity and after weight loss

AG Izquierdo, MC Carreira… - European Journal of …, 2022 - Wiley Online Library
DNA methylation levels of ACE2 were extracted from our data sets generated by the … DNA
methylation levels in ACE2 have been associated with increased vulnerability to COVID-19

Altered expression of DNA methyltransferases and methylation status of the TLR4 and TNF-α promoters in COVID-19

S Salem, R Mosaad, R Lotfy, M Elbadry - Archives of Virology, 2023 - Springer
… in COVID-19 patients and that DNA methylation is associated with decreased gene expression,
we predicted that methylation … of methylation of the promoters of both genes in COVID-19

Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity

AP Cheng, MP Cheng, W Gu, JS Lenz, E Hsu, E Schurr… - Med, 2021 - cell.com
… profiling methylation marks within circulating cell-free DNA (… -specific injury due to COVID-19.
The authors assessed the … cell-free DNA as an analyte to monitor and study COVID-19. …

[HTML][HTML] Methylation pathways and SARS-CoV-2 lung infiltration and cell membrane-virus fusion are both subject to epigenetics

L Pruimboom - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
… of the pathophysiology and illness severity of COVID-19. These mechanisms have been
identified … DNA methylation could be indicated as primary and/or secondary preventive options. …

Altered DNA methylation pattern contributes to differential epigenetic immune signaling in the upper respiratory airway of COVID-19 patients

M Govender, J Das, FR Hopkins, C Svanberg… - bioRxiv, 2024 - biorxiv.org
… the impact of COVID-19 on DNA methylation patterns … DNA methylation pattern in COVID-19
patients compared to healthy controls, characterized by 317 779 differentially methylated

[HTML][HTML] Epigenome-wide DNA methylation profiling of healthy COVID-19 recoverees reveals a unique signature in circulating immune cells

J Huoman, S Sayyab, E Apostolou, L Karlsson… - 2021 - europepmc.org
… Epigenome-wide DNA methylation patterns from COVID-19 … (PBMC) DNA was extracted
from uninfected controls, COVID-19 … analyses comprised differential DNA methylation, pathway …

Host methylation predicts SARS-CoV-2 infection and clinical outcome

IR Konigsberg, B Barnes, M Campbell… - Communications …, 2021 - nature.com
… In summary, the strong COVID-19-specific epigenetic signature in peripheral blood driven by
… Here we report DNA methylation profiling in conjunction with analysis using ML techniques …

Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression

C Konwar, R Asiimwe, AM Inkster, SM Merrill… - Epigenetics & …, 2021 - Springer
… In addition, we found differential DNA methylation patterns by COVID-19 status for genes,
such as NLRP2 and ACE2 in an exploratory analysis of an empirical data set reporting on …

Integrative Analysis of DNA Methylation and Gene Expression Data Identifies Potential Biomarkers and Functional Epigenetic Modules for SARS-CoV-2

L Li, L Hu, X Qiao, R Mo, G Liu, L Hu - Biochemical Genetics, 2023 - Springer
… the DNA methylation or gene expression profiles in COVID-19. However… DNA methylation
simultaneously and identifying functional epigenetic modules that are differentially methylated