Eleven telomere, epigenetic clock, and biomarker-composite quantifications of biological aging: do they measure the same thing?

DW Belsky, TE Moffitt, AA Cohen… - American journal of …, 2018 - academic.oup.com
… We studied 11 measures in total: telomere-length and erosion, 3 epigenetic-clocks and their
… The 71–cytosine-phosphate-guanine epigenetic clock and biomarker composites were …

Abstract P2-09-02: Evidence of accelerated epigenetic aging of breast tissues in patients with breast cancer compared to women without cancer

E Hofstatter, M Levine, Z Liu, T O'Meara, D Dalela… - Cancer Research, 2020 - AACR
… “epigenetic clocks” (also referred to as “epigenetic age”) have been developed to estimate
aging rates in tissues and cells. Using one of the original epigenetic clocksepigenetic clocks, …

Are the healthy vulnerable? Cytomegalovirus Seropositivity in healthy adults is associated with accelerated epigenetic age and immune Dysregulation

C Poloni, M Szyf, D Cheishvili… - The Journal of Infectious …, 2022 - academic.oup.com
… Prior to the COVID-19 pandemic we conducted … epigenetic age, accelerated aging, and
immune dysregulation in healthy, asymptomatic, older adults with CMV. Because the COVID-19

Epi-Clock: A sensitive platform to help understand pathogenic disease outbreaks and facilitate the response to future outbreaks of concern

C Ji, J Shao - medRxiv, 2022 - medrxiv.org
… , and accuracy of Epi-Clock with the true validation sets as … histones and protamines involved
in epigenetic regulation, we … improved the containment of COVID-19 but also contributed to …

Accelerated epigenetic aging in older adults with HIV disease: associations with serostatus, HIV clinical factors, and health literacy

SP Woods, AL Teixeira, LB Martins, GR Fries… - GeroScience, 2023 - Springer
… Second, we combined different epigenetic clocks into a single composite score and
confirmed its association with telomere length, a well-established marker of aging [24]. Third, we …

Epigenetic Clocks in Schizophrenia: Promising Biomarkers, Foggy Clockwork

S Akbarian - Biological Psychiatry, 2020 - biologicalpsychiatryjournal.com
… Next, the predictive validity of such type of epigenetic clock is tested in additional DNA
methylation datasets drawn from cohorts that are independent from the training set. In terms of …

Association of epigenetic clock with consensus molecular subtypes and overall survival of colorectal cancer

C Zheng, L Li, R Xu - Cancer Epidemiology, Biomarkers & Prevention, 2019 - AACR
… worse overall survival compared with CMS2 colorectal cancer (19). Taken together, our data
support epigenetic age acceleration as a promising prognostic factor for colorectal cancer. …

Epigenetic regulation of biological rhythms: an evolutionary ancient molecular timer

TJ Stevenson - Trends in Genetics, 2018 - cell.com
… on epigenetic plasticity has revealed a system that is highly dynamic and reversible. In this
Opinion, I propose an epigenetic clock … The hypothesis proposed is that an epigenetic clock

Redefining age-based screening and diagnostic guidelines: an opportunity for biological aging clocks in clinical medicine?

JC Nwanaji-Enwerem, WB Mair - The Lancet Healthy Longevity, 2022 - thelancet.com
… in ageing biomarkers, such as epigenetic clocks, … DNA methylation-based biomarkers and
the epigenetic clock … DNA methylation-based biomarkers and the epigenetic clock theory of …

[PDF][PDF] Host's DNA methylation alterations accompanying COVID-19 infection: a review article

LF Ali, FM Lafta, BM Khashman - researchgate.net
… upon COVID-19 infection. However, an association between COVID19 infection and reduce
expression of epigenetic … and epigenetic clocks prior to and following test-confirmed COVID-…