E Hofstatter, M Levine, Z Liu, T O'Meara, D Dalela… - Cancer Research, 2020 - AACR
… “epigeneticclocks” (also referred to as “epigenetic age”) have been developed to estimate aging rates in tissues and cells. Using one of the original epigeneticclocks … epigeneticclocks, …
… Prior to the COVID-19 pandemic we conducted … epigenetic age, accelerated aging, and immune dysregulation in healthy, asymptomatic, older adults with CMV. Because the COVID-19 …
… , and accuracy of Epi-Clock with the true validation sets as … histones and protamines involved in epigenetic regulation, we … improved the containment of COVID-19 but also contributed to …
… Second, we combined different epigeneticclocks into a single composite score and confirmed its association with telomere length, a well-established marker of aging [24]. Third, we …
S Akbarian - Biological Psychiatry, 2020 - biologicalpsychiatryjournal.com
… Next, the predictive validity of such type of epigeneticclock is tested in additional DNA methylation datasets drawn from cohorts that are independent from the training set. In terms of …
C Zheng, L Li, R Xu - Cancer Epidemiology, Biomarkers & Prevention, 2019 - AACR
… worse overall survival compared with CMS2 colorectal cancer (19). Taken together, our data support epigenetic age acceleration as a promising prognostic factor for colorectal cancer. …
TJ Stevenson - Trends in Genetics, 2018 - cell.com
… on epigenetic plasticity has revealed a system that is highly dynamic and reversible. In this Opinion, I propose an epigeneticclock … The hypothesis proposed is that an epigeneticclock …
… in ageing biomarkers, such as epigeneticclocks, … DNA methylation-based biomarkers and the epigeneticclock … DNA methylation-based biomarkers and the epigeneticclock theory of …
… upon COVID-19 infection. However, an association between COVID19 infection and reduce expression of epigenetic … and epigeneticclocks prior to and following test-confirmed COVID-…