… of patients with COVID-19 (5–8), with limited coverage of the human genome with loci selected
… Using unbiased whole-genome DNA methylation sequencing, we report for the first time …

… also downregulated in the severe group in sequencing results. Above all, the results … the
whole genome transcriptome to peripheral blood sample taken from severe and mild COVID-19 …

… Future studies based on whole genome methylation sequencing will provide the opportunity
to capture other outcome-associated DMRs and DMPs and provide a more comprehensive …

… Whole genome methylation sequencing revealed 39 differentially methylated regions (DMRs) …
28 unique differentially methylated positions (DMPs) in the genome discriminating patients …

… to analyze whole-blood DNA methylation data from COVID-19 … role of DNA methylation
in the development of COVID-19. The … High-throughput sequencing data provides extensive …

… differential DNA methylation sites that distinguish COVID-19 patients with … genome-wide
association studies (GWAS) in large populations of COVID-19 patients and genome sequencing …

… These factors, in combination with monocyte dysfunction reported in severe COVID-19
disease 47 , and the reduced methylation profile observed at cg03753191 in this study (Fig. 4C,G…

… COVID-19-induced circulating leukocytes DNA methylation … DMRs were uniformly distributed
along the entire genome (Fig. 1… and whole-genome methylation and RNA sequencing may …

… expression without altering the DNA sequence itself. It plays a … Differentially methylated
regions (DMRs) represent genomic … of methylation of a given CpG site depends on the genomic …

… and expression changes that are not dependent on the DNA sequence [3]. DNA … Full
size image To examine if changes in CpG methylation levels were associated with COVID-19 …