[HTML][HTML] Aging and options to halt declining immunity to virus infections

MÁ Palacios-Pedrero, ADME Osterhaus… - Frontiers in …, 2021 - frontiersin.org
… of the immune system triggered by aging, and address the effect of chronic viral infections,
effectiveness of vaccination of older adults and strategies to improve immune function in this …

Persistent viral infections and immune aging

S Brunner, D Herndler-Brandstetter, B Weinberger… - Ageing research …, 2011 - Elsevier
… types of persistent viral infections, especially CMV, influence the aging of the immune
system and highlight potential measures to prevent the age-related decline in immune function. …

Age-related decline in immunity: implications for vaccine responsiveness

R Kumar, EA Burns - Expert review of vaccines, 2008 - Taylor & Francis
… The cell components of the immune system are capable of mounting nonspecific, … or viral
infection) and specific or ‘adaptive’ responses. Figure 2 illustrates the changes in the immune

Enhancing immunity in viral infections, with special emphasis on COVID-19: A review

R Jayawardena, P Sooriyaarachchi… - Diabetes & Metabolic …, 2020 - Elsevier
… Low selenium status has been associated with an increased risk of mortality, poor
immune function, and cognitive decline, while a higher selenium concentration or selenium …

The role of immunity in susceptibility to respiratory infection in the aging lung

KC Meyer - Respiration physiology, 2001 - Elsevier
declining immune function with advancing age in an unselected population of elderly individuals,
many centenarians have fairly good immune … Influenza virus infection in the elderly has …

[HTML][HTML] Immunity and age: living in the past?

DL Woodland, MA Blackman - Trends in immunology, 2006 - cell.com
… This decline in immune responsiveness is a significant clinical problem because the elderly
become highly susceptible to infection and, … Immunological memory to viral infections. …

Respiratory-syncytial-virus infections, reinfections and immunity: a prospective, longitudinal study in young children

FW Henderson, AM Collier, WA Clyde Jr… - New England Journal …, 1979 - Mass Medical Soc
… To better understand acquired immunity to respiratory-syncytial-virus infections, we analyzed
Immunity was measured in terms of failure to become infected or reduction in severity of …

Immune responses to influenza virus infection

J Kreijtz, RAM Fouchier, GF Rimmelzwaan - Virus research, 2011 - Elsevier
… Later in life functionality of the immune system declines, a phenomenon known as
immunosenescence. Elderly have smaller B cell populations and their T cell populations have …

Decline in varicella-zoster virus (VZV)–specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine

MJ Levin, JG Smith, RM Kaufhold… - … Journal of infectious …, 2003 - academic.oup.com
… In contrast to smaller, better-studied viruses, such as human immunodeficiency virus (HIV), …
control of VZV infection than they do in some other viral infections (eg, HIV infection) [9, 10] …

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

EJ Yager, M Ahmed, K Lanzer, TD Randall… - The Journal of …, 2008 - rupress.org
virus infection model to address the relationship between the naturally occurring age-associated
decline in … of aged mice to de novo influenza virus infection exhibited a markedly altered …