… Impact of Lard versus Fish-Oil Diet on Gut Microbiota To assess how the dietary fat sources
affects the microbiota, we fed mice isocaloric diets that differed only in fat composition (either …

… TLR signaling in the mucosa can also induce production of inflammasomes, multiprotein
oligomers responsible for the activation of inflammatory responses. Inflammasomes activate a …

… Two recent studies have reported that genetic deficiency of MyD88, a TLR signaling adaptor
molecule, reduces aortic atherosclerosis (∼60%) in Apoe −/− mice fed high-fat diet [10], [11]…

… for TLR-4 signalling [51]. In addition, the incorporation of DHA into lipid membrane disrupts
the translocation of TLR-4 into lipid raft, thus inhibiting the TLR-4 signalling pathway [50, 55]. …

… [132] demonstrated how SFA in lard altered the gut microbial ecology to promote obesity
and WAT inflammation through TLR signaling and MCP-1. Eleven to 14-week-old mice were …

… TLR-4 is not strong enough to induce NF-κB and COX-2 pathways [41]. The type of dietary fat
… in vivo and in vitro experiments on TLRs signaling pathways. The doses used ranged from …

… production by activating TLR-4 and NF-κB signaling. Additionally, … Dietary fat was considered
only as a source of energy until 1929 when George and Mildred Burr reported that dietary …

… infection may be modified by the types of dietary fat consumed. … in cellular lipids are
sensitively affected by those of dietary fat. … Some lipids interrupt TLR signaling by interfering the …

… Although these inflammatory effects of certain dietary fats are increasingly appreciated,
the ubiquity of the body's inflammatory and metabolic response to foods poses a mystery. …

… In our HLP model, the serum lipids also showed the natural susceptibility of rabbits to diet-induced
HLP. The HFD-fed rabbits developed markedly higher levels of TG, TCHO, LDL-C, …