Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity

S De, R Shaknovich, M Riester, O Elemento… - PLoS …, 2013 - journals.plos.org
… Although these diseases share many mutant alleles, the underlying cause of the different
phenotypes remains unclear. We show that direct comparison of DNA methylation patterning …

A machine learning approach utilizing DNA methylation as an accurate classifier of COVID-19 disease severity

S Bowler, G Papoutsoglou, A Karanikas… - Scientific Reports, 2022 - nature.com
… unique methylation sites with the power to discern individuals with severe COVID-19 disease.
… of the utility of DNA methylation in COVID-19 disease pathology and serve as a platform to …

DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

M Magalhães, I Rivals, M Claustres, J Varilh… - Clinical …, 2017 - Springer
… Thus, we concluded that loss of DNA methylation at EDNRA was a consequence rather
than a cause of lung disease severity. DNA methylation levels at GSTM3 were associated with …

Blood-derived DNA methylation signatures of Crohn's disease and severity of intestinal inflammation

HK Somineni, S Venkateswaran, V Kilaru… - Gastroenterology, 2019 - Elsevier
… to complicated disease, which includes stricturing (B2), within 5 years. We analyzed DNA
methylation patterns in blood samples of pediatric patients with Crohn's disease at diagnosis …

[HTML][HTML] Altered DNA methylation and gene expression predict disease severity in patients with Aicardi-Goutières syndrome

J Garau, A Charras, C Varesio, S Orcesi, F Dragoni… - Clinical …, 2023 - Elsevier
Disease-causing mutations are present in genes associated with innate antiviral responses.
Disease presentation and severity … This study investigated DNA methylation signatures in …

[HTML][HTML] DNA methylation changes in inflammatory bowel disease

PS Karatzas, M Gazouli, M Safioleas… - … quarterly publication of …, 2014 - ncbi.nlm.nih.gov
… , DNA methylation has been related to many different clinical aspects, such as disease severity,
disease duration, disease … Is the level of DNA methylation or the DNA methylation itself …

Blood global DNA methylation is decreased in non-severe chronic obstructive pulmonary disease (COPD) patients

A Zinellu, E Sotgiu, AG Fois, E Zinellu, S Sotgia… - Pulmonary …, 2017 - Elsevier
… significant associations between DNA methylation and disease severity in COPD … DNA
methylation and early COPD disease in healthy controls and COPD patients with mild disease. …

DNA methylation and human disease

KD Robertson - Nature Reviews Genetics, 2005 - nature.com
DNA methylation patterns in human diseases. It should be noted that I focus only on those
diseases for which defective DNA methylation … correlates with disease severity and metastatic …

[HTML][HTML] DNA methylation in human diseases

Z Jin, Y Liu - Genes & diseases, 2018 - Elsevier
… progression of many common diseases. We discuss some recent findings on one representative
epigenetic modification, DNA methylation, in some common diseases. While many new …

Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome

C Brückmann, A Di Santo, KN Karle, A Batra… - Epigenetics, 2016 - Taylor & Francis
… In addition, we studied GDAP1 DNA methylation after 3 weeks of participating in an inpatient
alcohol treatment program to elucidate whether GDAP1 DNA methylation could also serve …