Is depression associated with accelerated aging? Mechanisms and implications

D Lindqvist, NM Simon, OM Wolkowitz - Neurobiology of Depression, 2019 - Elsevier
… Depression is associated with early mortality and with an … by evidence that telomerase
mediates neurotrophic effects of brain-derived neurotrophic factor (BDNF) in embryonic and early

[HTML][HTML] Accelerated aging in the brain, epigenetic aging in blood, and polygenic risk for schizophrenia

J Teeuw, APS Ori, RM Brouwer, SMC de Zwarte… - Schizophrenia …, 2021 - Elsevier
… signs of accelerated aging in cognitive and physiological domains. Both schizophrenia and
accelerated aging, … We found suggestive evidence of correlations between polygenic risk for …

Could accelerated aging explain the excess mortality in patients with seropositive rheumatoid arthritis?

CS Crowson, KP Liang, TM Therneau… - … : Official Journal of …, 2010 - Wiley Online Library
… Although this is a standard approach, compelling evidence suggests biologic changes, such
as seropositivity, often occur years earlier than the clinical manifestations of RA. Therefore, …

[HTML][HTML] Inflammatory cytokines and comorbidity development in breast cancer survivors versus noncancer controls: evidence for accelerated aging?

CM Alfano, J Peng, RR Andridge… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
evidence for an accelerated aging phenotype in breast cancer survivors characterized by the
accumulation of excess comorbidities relative to peers of the same age … accumulation early

Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood

EJ Hamlat, AA Prather, S Horvath… - Developmental …, 2021 - Wiley Online Library
… While accelerated aging in childhood has been related to earlier age of menarche (Binder et
al., 2018), age … Recent evidence suggests that early life threat (eg, physical abuse), but not …

[HTML][HTML] Is there any evidence of premature, accentuated and accelerated aging effects on neurocognition in people living with HIV? A systematic review

HL Aung, M Aghvinian, H Gouse, RN Robbins… - AIDS and Behavior, 2021 - Springer
… -related conditions such as cardiovascular diseases (CVD), frailty, chronic renal disease
and stroke were observed at a higher rate and at an earlier age among PLHIV than age-…

Early adversities accelerate epigenetic aging into adulthood: a 10‐year, within‐subject analysis

WE Copeland, L Shanahan… - Journal of Child …, 2022 - Wiley Online Library
accelerated aging when describing advanced age. Importantly, multiple observations allow
for tracking change in DNAm over time in response to these early … provides little evidence to …

Early-life exposure to tobacco, genetic susceptibility, and accelerated biological aging in adulthood

F Cui, L Tang, D Li, Y Ma, J Wang, J Xie, B Su… - Science …, 2024 - science.org
… on accelerated aging were stronger in participants aged ≤50 years than in participants … In
summary, we provided evidence based on a large-scale epidemiological survey that exposure …

Accelerated aging and male homosexuality: Australian evidence in a continuing debate

KC Bennett, NL Thompson - Journal of Homosexuality, 1991 - Taylor & Francis
… the issue of accelerated aging among gay men. We believe the earlier research has not …
Accelerated aging among homosexual men can be considered only by examining the total …

SIRTain regulators of premature senescence and accelerated aging

S Ghosh, Z Zhou - Protein & cell, 2015 - academic.oup.com
… of premature cellular senescence and accelerated aging. The roles of … aging mechanisms.
Also, the latest findings on sirtuins which might have potential effects in the process of aging