[HTML][HTML] Discovery and validation of new potential biomarkers for early detection of colon cancer

X Solé, M Crous-Bou, D Cordero, D Olivares, E Guinó… - PLoS …, 2014 - journals.plos.org
… and further validation of biomarkers for early detection of colon cancer that identifies
COL10A1 protein levels in serum as a potential diagnostic candidate to detect both adenoma …

[HTML][HTML] Discovery and validation of breast cancer early detection biomarkers in preclinical samples

CI Li - Hormones and Cancer, 2011 - Springer
… at discovering and validating breast cancer early detection … to validate the numerous other
candidates we discovered, most … candidates based on their discovery odds ratios and p values…

The early detection research network: A national infrastructure to support the discovery, development, and validation of cancer biomarkers

S Srivastava, PD Wagner - Cancer Epidemiology, Biomarkers & Prevention, 2020 - AACR
Early Detection Research Network (EDRN) is to discover, develop, and validate biomarkers
and imaging methods to detect early-… to the discovery and validation of biomarkers to detect

[HTML][HTML] Discovery and validation of methylation signatures in circulating cell-free DNA for early detection of esophageal cancer: a case-control study

G Qiao, W Zhuang, B Dong, C Li, J Xu, G Wang, L Xie… - BMC medicine, 2021 - Springer
… of the early detection classifier was validated in an independent validation cohort. … to May
2020 to further validate the performance of the early detection classifier independently. Healthy …

[HTML][HTML] Discovery and validation of FBLN1 and ANT3 as potential biomarkers for early detection of cervical cancer

Y Hao, M Ye, X Chen, H Zhao, A Hasim, X Guo - Cancer cell international, 2021 - Springer
… Therefore, regular screening is critical for effective early detection and treatment of cervical
cancer [7, 8]. In current clinical practice in China, screening rests on morphological changes …

Biomarker discovery and validation: technologies and integrative approaches

SE Ilyin, SM Belkowski, CR Plata-Salamán - Trends in biotechnology, 2004 - cell.com
discovery, characterization, validation and application of biomarkers. For example, the low
specificity of PSA for detecting … specificity in the early detection or diagnosis of this disease [ …

Leveraging biospecimen resources for discovery or validation of markers for early cancer detection

SD Schully, DM Carrick, LE Mechanic… - Journal of the …, 2015 - academic.oup.com
Validation of early detection cancer biomarkers has proven … assess the validity of some early
detection biomarkers. With this … The goal was to advance early detection cancer research by …

[HTML][HTML] Discovery and validation of methylation signatures in blood-based circulating tumor cell-free DNA in early detection of colorectal carcinoma: a case–control …

J Sui, X Wu, C Wang, G Wang, C Li, J Zhao, Y Zhang… - Clinical …, 2021 - Springer
… Together our findings showed that ctDNA methylation markers were promising in the
early detection of CRC. Further validation of this model is warranted in prospective studies. …

Biomarker discovery study of inflammatory proteins for colorectal cancer early detection demonstrated importance of screening setting validation

J Qian, K Tikk, S Werner, Y Balavarca, M Saadati… - Journal of clinical …, 2018 - Elsevier
… much poorer in a further validation in a true screening setting. Our results underscore the
necessity to validate biomarkers for CRC early detection discovered in CRC cases from clinics …

[HTML][HTML] Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis

A Sutherland, M Thomas, RA Brandon, RB Brandon… - Critical care, 2011 - Springer
… by early hyper-inflammation followed by severe and protracted immunosuppression,
suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a …