… at discovering and validating breast cancer earlydetection … to validate the numerous other candidates we discovered, most … candidates based on their discovery odds ratios and p values…
S Srivastava, PD Wagner - Cancer Epidemiology, Biomarkers & Prevention, 2020 - AACR
… EarlyDetection Research Network (EDRN) is to discover, develop, and validate biomarkers and imaging methods to detectearly-… to the discovery and validation of biomarkers to detect …
G Qiao, W Zhuang, B Dong, C Li, J Xu, G Wang, L Xie… - BMC medicine, 2021 - Springer
… of the earlydetection classifier was validated in an independent validation cohort. … to May 2020 to further validate the performance of the earlydetection classifier independently. Healthy …
Y Hao, M Ye, X Chen, H Zhao, A Hasim, X Guo - Cancer cell international, 2021 - Springer
… Therefore, regular screening is critical for effective earlydetection and treatment of cervical cancer [7, 8]. In current clinical practice in China, screening rests on morphological changes …
SE Ilyin, SM Belkowski, CR Plata-Salamán - Trends in biotechnology, 2004 - cell.com
… discovery, characterization, validation and application of biomarkers. For example, the low specificity of PSA for detecting … specificity in the earlydetection or diagnosis of this disease [ …
SD Schully, DM Carrick, LE Mechanic… - Journal of the …, 2015 - academic.oup.com
… Validation of earlydetection cancer biomarkers has proven … assess the validity of some early detection biomarkers. With this … The goal was to advance earlydetection cancer research by …
J Sui, X Wu, C Wang, G Wang, C Li, J Zhao, Y Zhang… - Clinical …, 2021 - Springer
… Together our findings showed that ctDNA methylation markers were promising in the earlydetection of CRC. Further validation of this model is warranted in prospective studies. …
J Qian, K Tikk, S Werner, Y Balavarca, M Saadati… - Journal of clinical …, 2018 - Elsevier
… much poorer in a further validation in a true screening setting. Our results underscore the necessity to validate biomarkers for CRC earlydetectiondiscovered in CRC cases from clinics …
A Sutherland, M Thomas, RA Brandon, RB Brandon… - Critical care, 2011 - Springer
… by early hyper-inflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for earlydetection, within a …