CM Koch, W Wagner - Aging (Albany NY), 2011 - ncbi.nlm.nih.gov
… This process is associated with epigenetic modifications such as methylation changes at … an Epigenetic-Aging-Signature which is applicable for many tissues to predict donor age. DNA-…
… Epigenetic clocks have proven themselves to be accurate at predicting chronological age (chAge), which is commonly referred to as DNAm age or epigeneticage (eAge). When …
S Bocklandt, W Lin, ME Sehl, FJ Sánchez… - PloS one, 2011 - journals.plos.org
… The identification of specific epigenetic patterns highly correlated with age has the potential to influence our understanding of ageing in health and disease. Specifically, it could lead to …
… On the other hand, Horvath’s agepredictor outperformed our predictor in samples from the brain. Their performance in other tissues (breast, liver, adipose, and muscle) was similar, …
… For this purpose, we use epigenetic surrogates (EpiScores) for 109 plasma proteins and the … the current best epigenetic predictors of survival. We test this bAge predictor in four external …
… Moreover, the accuracy of our 65 CpG model even outperformed the accuracy of age-predictions using the epigeneticaging signatures with 353 CpGs [19] or 71 CpGs [17], often …
A Montesanto, P D'Aquila, V Lagani… - Journal of forensic …, 2020 - Wiley Online Library
… The aging process significantly affects most of the … an epigenetic model for ageprediction was validated in a sample of the Italian population. However, its applicability to advanced ages …
… the aging process in the DNAm landscape to show how epigeneticage clocks evolved from a chronological age … including epigeneticage estimator (epigeneticage clock), epigenetic …
… the hypothesis that an epigeneticpredictor for biological age might be trained on face-age as a surrogate for biological age rather than on chronological age. Our data demonstrate that …