[HTML][HTML] Development and optimization of quercetin-loaded PLGA nanoparticles by experimental design

LR Tefas, I Tomuţă, M Achim, L Vlase - Clujul Medical, 2015 - ncbi.nlm.nih.gov
… Consequently, the administration of PLGA nanoparticles is associated with a minimal …
Box-Behnken experimental design was successfully used in order to obtain QU-nanoparticles with …

Synthesis of hesperetin-loaded PLGA nanoparticles by two different experimental design methods and biological evaluation of optimized nanoparticles

D Duranoğlu, D Uzunoglu, B Mansuroglu… - …, 2018 - iopscience.iop.org
… of hesperetin-loaded PLGA nanoparticles were investigated using two different experimental
design methods. With the use of the Plackett–Burman design, major process parameters …

Optimization of ciprofloxacin complex loaded PLGA nanoparticles for pulmonary treatment of cystic fibrosis infections: Design of experiments approach

NG Türeli, AE Türeli, M Schneider - International journal of pharmaceutics, 2016 - Elsevier
… In this study, ciprofloxacin loaded PLGA nanoparticles were prepared by nanoprecipitation
method by utilizing MicroJet Reactor (MJR) to overcome the bottlenecks of the pulmonary …

Design of experiment (doe) for optimization of PLGA nanoparticles

R Gupta, H Xie, M Sarkar, Y Chen - The FASEB Journal, 2022 - Wiley Online Library
PLGA NPs were prepared by double emulsion technique. Aqueous drug solution (W1) was
experimental runs, time, and cost. Similar DOE approaches can be used for other PLGA-…

Biocompatible stabilizers in the preparation of PLGA nanoparticles: a factorial design study

J Vandervoort, A Ludwig - International journal of pharmaceutics, 2002 - Elsevier
… of concentrations of stabilizers and the particles zeta potential value, the experimental
design was expanded to a central composite design for the two most promising stabilizers. …

Nimodipine loaded PLGA nanoparticles: formulation optimization using factorial design, characterization and in vitro evaluation

AK Mehta, KS Yadav, KK Sawant - Current drug delivery, 2007 - ingentaconnect.com
PLGA nanoparticles of Nimodipine as a sustained release delivery system. It was hypothesized
that the developed PLGA … NIM loaded NPs using two grades of PLGA (50:50 and 85:15). …

Formulation and optimization of nonionic surfactants emulsified nimesulide-loaded PLGA-based nanoparticles by design of experiments

CTS Turk, UC Oz, TM Serim, C Hascicek - Aaps pharmscitech, 2014 - Springer
… NMS-loaded PLGA NPs by using a 3 2 factorial design. Factorial experimental designs
allow for the rapid and efficient screening of design variables with a limited number of planned …

Experimental design and multivariate analysis for optimizing poly (d, l-lactide-co-glycolide)(PLGA) nanoparticle synthesis using molecular micelles

GM Ganea, CM Sabliov, AO Ishola… - … of nanoscience and …, 2008 - ingentaconnect.com
… In the present study, PLGA nanoparticles were synthesized by use of an emulsification
solvent evaporation method using molecular micelles poly-SUS, poly-SUG and polyL-SULV as …

Formulation optimization of etoposide loaded PLGA nanoparticles by double factorial design and their evaluation

KS Yadav, KK Sawant - Current drug delivery, 2010 - ingentaconnect.com
… between an experimental response and a set of input variables. RSM sets a mathematical
trend in the experimental design for determining the optimum level of experimental factors …

A robust systematic design: optimization and preparation of polymeric nanoparticles of PLGA for docetaxel intravenous delivery

P Rafiei, A Haddadi - Materials Science and Engineering: C, 2019 - Elsevier
… In the present work, an experimental design based on Taguchi robust method was used
for optimization of PLGA nanoparticles loaded with docetaxel. The L16 Taguchi …