… folate chemistry that is often overlooked, and point out various missing links and underdeveloped
areas in folate metabolism … of folate chemistry, an important aspect of folate metabolism …

… Folate acts directly to produce antioxidant effects, … Folate acts indirectly to lower homocysteine
levels and insure optimal functioning of the methylation cycle. Folate metabolism provides …

… Although several well validated metabolic and genomic biomarkers for folate deficiency
exist… impaired folate metabolism increases risk for developmental anomalies and disease is …

… Figure 2 Intracellular folate metabolism. Simplified scheme of intracellular folate metabolism
and one… in intraluminal folate hydrolysis (GCPII, glutamate carboxypeptidase II), intracellular …

… In advanced chronic kidney disease folate metabolism must be considered due to serious
… In end stage kidney disease, an insignificant proportion of patients, diminished serum folate …

… folate metabolism and of the metabolic consequences of derangements in folate metabolism.
… of the mechanisms by which folate is handled in the body and how tissue folate levels and …

… Folate metabolism, which supports a broader set of transformations known as one-carbon
(1C) metabolism, is a universal metabolic process that serves to activate and transfer 1C units …

… Our aim is to describe what happens to folate homeostasis in gastrointestinal health and
disease, analyzing the alterations of folate metabolism in some specific conditions of intestinal …

… as being separate from folate metabolism. In this article, the essentials of folate metabolism
are reviewed. The focus will be on oral folate bioavailability, intracellular pathways of folate …

… recent studies aimed at elucidating the role of folate, B12, and methionine in one-carbon
metabolism during normal cellular processes and in the context of disease progression. …