… Whether cellular senescence is rather friend or foe most likely depends on accompanying
lesions, first of all in apoptotic response programs, and on the cellular context. In further …

… cell types and contributes to age-associated diseases. In particular, cellular senescence may
… However, the role cellular senescence plays in the pathophysiology of acute inflammatory …

Title: The life and times of cellular senescence in skeletal muscle: friend or foe for 1 homeostasis
and adaptation? 2 3 Authors Page 1 Title: The life and times of cellular senescence in …

… Cell senescence denotes cell growth arrest in response to continuous replication or … of
cell senescence besides ceased cell proliferation. First, the senescent cell exhibits senescence-…

… Senescence can also lead to the removal of potentially … for NF-κB in tumor suppression via
cellular senescence and suggest that … , NF-κB can indeed promote senescence growth arrest. …

… Here, we review in detail the mechanisms by which cellular senescence contributes to
cancer development and the side effects of cancer therapies. We also review how …

… cell survival and proliferation to triggering tumor suppressor responses such as cell differentiation,
cell senescence, … to be of primary importance in determining the final cellular outcome. …

… Furthermore, there are no universally accepted markers of cell senescence (7). Finally,
cell senescence is also a double-edged sword as these cells are needed in the case of some …

… senescence. Several other pathways have recently been implicated in mediating senescence
and the senescent … that underlie cellular senescence and the senescence associated …

… In this review, we briefly cover the effects of oxidative stress and cellular senescence on
cancer, cardiovascular diseases and neurodegenerative disorders such as Alzheimer’s Disease …