Genome-scale DNA methylation analysis

SD Fouse, RP Nagarajan, JF Costello - Epigenomics, 2010 - Taylor & Francis
… Considering the 29 million CpGs in the haploid genome, DNA methylation patterns in normal
human cells are largely unexplored Citation[10]. Several general methylation patterns are …

Genome-scale DNA methylation maps of pluripotent and differentiated cells

A Meissner, TS Mikkelsen, H Gu, M Wernig, J Hanna… - Nature, 2008 - nature.com
genome-wide distribution of DNA methylation, how it changes during cellular differentiation
and how it relates to histone methylation … analysis of genome-scale DNA methylation profiles …

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

H Gu, C Bock, TS Mikkelsen, N Jäger, ZD Smith… - Nature …, 2010 - nature.com
… status of essentially all nonrepetitive regions in the genome at single-… genome-scale DNA
methylation analysis 3,4 . Here we show that RRBS is highly appropriate for DNA methylation

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling

H Gu, ZD Smith, C Bock, P Boyle, A Gnirke… - Nature protocols, 2011 - nature.com
… To help guide decision-making for some of the genome-scale approaches, we have recently
completed an extensive comparison of four commonly used genome-wide DNA methylation

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

T Hinoue, DJ Weisenberger, CPE Lange… - Genome …, 2012 - genome.cshlp.org
… Here we performed comprehensive genome-scale DNA methylation profiling of 125
colorectal tumors and 29 adjacent normal tissues. We identified four DNA methylation–based …

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

SA Selamat, BS Chung, L Girard, W Zhang… - Genome …, 2012 - genome.cshlp.org
… Here we performed genome-scale DNA methylation profiling … genome-scale verification
on an independent set of tissues. We identified 766 genes showing altered DNA methylation

[HTML][HTML] Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

J Klughammer, D Romanovskaia, A Nemc… - Nature …, 2023 - nature.com
… To investigate DNA methylation beyond the human genome and in the broad context of
vertebrate evolution, we established genome-scale DNA methylation profiles at single-base …

[HTML][HTML] Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals 5 distinct subtypes of colorectal adenocarcinomas

L Fennell, T Dumenil, L Wockner, G Hartel… - Cellular and molecular …, 2019 - Elsevier
… silencing, the relationship between DNA methylation and … the extent and spectrum of DNA
methylation changes occurring in … of DNA methylation in the modulation of gene transcription, …

Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips

VA Naumov, EV Generozov, NB Zaharjevskaya… - Epigenetics, 2013 - Taylor & Francis
… person-specific DNA methylation and its possible … DNA methylation experiments could
be an artifact related to the field cancerization effect. Our results showed that DNA methylation

[HTML][HTML] Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture

MR Choi, YH In, J Park, T Park, KH Jung… - … & molecular medicine, 2012 - nature.com
genome-scale DNA and miRNA promoter methylation patterns of MSCs between early and
late passages. We observed that genes exhibiting methylation … were more gene promoters …