Catch me if you can: SARS-CoV-2 detection in brains of deceased patients with COVID-19

S Frank - The Lancet Neurology, 2020 - thelancet.com
SARS-CoV-2 brain infection as opposed to reflecting sequelae of an overstimulated systemic
immune response is of high clinical importance. Whereas the first scenario would support …

[HTML][HTML] SARS-CoV-2 pathophysiology and assessment of coronaviruses in CNS diseases with a focus on therapeutic targets

J Vallamkondu, A John, WY Wani, SP Ramadevi… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… Elevated IP-10 and Mig might have affected the T-cell immune system and helped the
SARS-CoV to enter into the brain tissue with the aid of CD68 + monocytes/macrophages and CD3 …

The SARS-CoV-2 and mental health: From biological mechanisms to social consequences

D Szcześniak, A Gładka, B Misiak, A Cyran… - Progress in Neuro …, 2021 - Elsevier
SARS-CoV-2 on the CNS and mental health outcomes. We describe neurobiology of the
virus… It has been documented that the SARS-CoV-2 can pass through the blood-brain barrier, or …

Infection mechanism of SARS-COV-2 and its implication on the nervous system

EE Reza-Zaldívar, MA Hernández-Sapiéns… - Frontiers in …, 2021 - frontiersin.org
… , substantia nigra, and the brain stem (35), supporting the SARS-CoV-2 potential to infect cells
… where the SARS-CoV-2 is detected within neuronal soma and neurites using human brain

Infection of human cells by SARS-CoV-2 and molecular overview of gastrointestinal, neurological, and hepatic problems in COVID-19 patients

M Rahban, A Stanek, A Hooshmand… - Journal of Clinical …, 2021 - mdpi.com
… symptoms indicates the lymph vessels around the GI tract, vascular system, or ENS (gut–brain
axis) to be the most likely entry route for SARS-CoV-2 to the brain and CNS [7,88]. …

[PDF][PDF] Sars-COV-2 infection leads to neurodegenerative or neuropsychiatric diseases

A Dubey, NS Ghosh, VPS Rathor, S Patel… - International Journal of …, 2022 - academia.edu
brain barrier inflammation, which supports our RNA-seq finding Several SARS-CoV-2 entry
genes have been discovered in brain … They were screened for SARS-CoV2 using RNA and …

Brainstem neuropathology in two cases of COVID-19: SARS-CoV-2 trafficking between brain and lung

G Bulfamante, T Bocci, M Falleni, L Campiglio… - Journal of …, 2021 - Springer
Our findings show SARS-CoV-2-related brainstem involvement. In our cases (Fig. 2.Ia–b),
the … The immunohistochemical evidence showing Sars-CoV-2 in the brainstem and astroglial …

Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
… (E) Finally, once the virus reaches the brain stem, it can spread to the brain through …
CRS is a systemic inflammatory response that can be triggered by SARS CoV-2 infection, …

Strong ACE-2 expression in the choroidal vessels: do high choroid plexuses serve as a gateway for SARS-CoV-2 infection on the human brain?

M Piras, F Cau, M Manchia, P Paribello… - European Review for …, 2022 - iris.unica.it
… Here we propose a new function for choroid plexuses, regarding brain involvement in
subjects infected by SARS-CoV-2. Our findings suggest that SARS-CoV-2 can reach the …

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

J Wenzel, J Lampe, H Müller-Fielitz, R Schuster… - Nature …, 2021 - nature.com
SARS-CoV-2 can infect brain endothelial cells To approach the question of whether SARS-CoV-2
can infect brain … are known to facilitate the entry of SARS-CoV-2 in host cells, namely …