P Wang, L Jin, M Zhang, Y Wu, Z Duan, Y Guo… - Nature Biomedical …, 2023 - nature.com
… probe the effects of SARS-CoV-2 infection on the humanbrain using a lung–brain MPS. Our … In summary, we studied the effects of SARS-CoV-2 infection on the humanbrain in an organ…
L Bauer, BM Laksono, FMS de Vrij, SA Kushner… - Trends in …, 2022 - cell.com
… contribute to the neuroinvasiveness of SARS-CoV-2. Other possibilities for neuroinvasion of SARS-CoV-2 are through hematogenous spread via either the blood–brain barrier (BBB) or …
… from the SARS-CoV-2 viral spike protein on primary humanbrain … brain tissue, we show that the angiotensin converting enzyme 2 or ACE2 (a known binding target for the SARS-CoV-2 …
R Khaddaj-Mallat, N Aldib, M Bernard… - Neurobiology of …, 2021 - Elsevier
… Although brain pericytes were recently shown to abundantly … to SARS-CoV-2 S protein is still to be elucidated. Using cell-based assays, we found that ACE2 expression in humanbrain …
GE Serrano, JE Walker, R Arce, MJ Glass, D Vargas… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… Two human coronaviruses, strains 229E and OC43, were … , of 90 humanbrains obtained from multiple brain banks … that have occurred in humans infected with SCV2 28 – 35 , it is …
… and brain damage. Then, we analyzed and described the possible mechanisms causative of brain injury after SARS-CoV-2 infection. We proposed that potential routes of SARS-CoV-2 …
… 401 cases who tested positive for infection with SARS-CoV-2 between their two scans—with … brain size in the SARS-CoV-2 cases. The participants who were infected with SARS-CoV-2 …
… To investigate the susceptibility of humanbrain cells to SARSCoV-2 infection, we tested various hiPSC-derived neural cells in monolayer cultures and region-specific brain organoids …
… Despite reports of SARS-CoV-2 detection in the brain and cerebrospinal fluid of COVID-19 patients, it is still unclear whether the virus can infect the central nervous system, and which …