X Liu, RI Nurieva, C Dong - Immunological reviews, 2013 - Wiley Online Library
… STAT5 efficiently inhibits Tfh differentiation by suppressing the expression of Tfh-associated genes … Further understanding of Tfhcell regulation may offer ways to target various immune …
M Almanan, J Raynor, I Ogunsulire, A Malyshkina… - Science …, 2020 - science.org
… cells that accumulate with age bore markers of Tfhcells, so, for clarity, we will refer to them as Tfh10 cells… FoxP3 − CD4 + T cells, we blocked IL-6 after Tfhcells were formed in aged mice …
… Our data suggest that human T FH X13 cell differentiation may be a key factor in converting Treg-mediated immunesuppression to de novo activation of adaptive antitumor humoral …
A Pratama, CG Vinuesa - Immunology and cell biology, 2014 - Wiley Online Library
… c-Maf specifically in immunecells exhibited defective TFHcell differentiation in vivo. The c-… -2 acting through STAT5 and IL-10 can suppressTFHcell development at least in mice. , 89 …
AC Olatunde, JS Hale, TJ Lamb - Trends in immunology, 2021 - cell.com
… The heterogeneity of Tfhcells underscores their ability to modulate different humoral immune … Regulatory T follicular (Tfr) cells can suppress T–B cell interactions through cytotoxic T …
… This suggested that anti-CTLA-4 antibody treatment preferentially expanded tetramer-binding Tfhcells out of proportion with their matching Tfr suppressive population, while PD1 + and …
… for Tfollicularhelpercells that parallels the development of other CD4 + T-cell lineages but … Treg cellssuppress the sensitization and effector phases of allergic reactions through the …
… To analyze the role of mast cells in UV-induced immunesuppression, we reconstituted mast … We find that mast cellssuppressTfhcell generation, the formation of GCs, and Ab …
H Wu, Y Chen, H Liu, LL Xu, P Teuscher… - European journal of …, 2016 - Wiley Online Library
… whether Tfr cells could suppress the GCB cell response. … Tfhcells, this result of unchanged GCB cell numbers in the absence of Tfr cells was observed after multiple types of immune …