… with activation of vascular endothelial cells and thence the recruitment of highly toxic
neutrophils and inflammatory activated platelets into the alveolar space. Activated vascular …

… pathway is activated by SARS-CoV-2 … SARS-CoV-2 induced inflammation, we evaluated
the effects of a specific IKK inhibitor (BI-605906) on the transcriptional profile of genes activated …

… -triggered inflammatory responses are currently unknown. Here we report that SARS-CoV-2
infection activates caspase-8 to trigger cell apoptosis and inflammatory cytokine processing …

… Here, we review the mechanisms by which SARS-CoV-2 both activates and antagonizes
the IFN and inflammatory response following infection, how a dysregulated cytokine and …

… responses include various methods to block FcR activation. … inflammation is likely a leading
cause of fatality in SARS-CoV-2 … inflammatory responses in order to reduce mortality (Fig. 2). …

… activation is a major mediator of inflammation 7 , we examined the blood of patients infected
with SARS-CoV-2 for inflammasome activation … , monocytes had taken up SARS-CoV-2 virus …

… Inflammatory pathways associated with SARS-CoV-2 during … SARS-CoV-2 in the extracellular
milieu or endosomes and mediate the inflammatory signaling leading to the activation and …

… Here, we investigated direct inflammatory functions of major structural proteins of SARS-
CoV… mechanism for the inflammatory response induced by SARS- CoV- 2. We demonstrate that …

… To further confirm the ability of SARS-CoV-2 proteins to activate inflammatory … to activate
inflammatory signaling pathways, we stimulated BMDMs with purified E protein from SARS-CoV-…

… Here, we report that 2 short sequences within the ssRNA genome of SARS-CoV-2 activate
the production of type I IFNs and the T cell–activating ability of human DCs by triggering …