… by cytokine dysregulation, which is an increase of proinflammatory cytokines and reduction
of anti-inflammatory cytokines, leading to a chronic low-grade inflammatory state. The …

… The mechanisms that drive accelerated aging or comorbidity burden and … inflammatory
cytokines and comorbidity development. Although there were no baseline differences in cytokines …

… cytokines. Westendorp has suggested that the balance between proinflammatory and
antiinflammatory cytokines … , a major role of cytokines is in their ability to accelerate the loss of …

… ), nuclear factor κB, inflammatory cytokines with MDD. Major depression also is characterized
by significantly lower concentration of antioxidants (zinc, coenzyme Q10, PON1). Since, …

… This cascade of events, coupled with a milieu of increased inflammatory cytokines, may
lead to accelerated cellular aging via effects on the telomere/telomerase maintenance system. …

… Therefore, we measured the expression of several inflammatory cytokines in kidney that
have been shown to be induced in senescent cells: IL-6, IL-1β and IL-8. As shown in Fig. 3A, IL-…

… In this review, we explore the additional possibility that “accelerated aging” in depression …
inflammatory cytokines, such as IL-6, are associated with the activation of central inflammatory …

… the inflammatory cytokine IL-6 is elevated in a pathological acute situation, such as hypoxia.
The combined induction of both inflammatory cytokines, … in aged individuals; these cytokines …

… of “accelerated aging,” which leads to stromal inflammation and … a unified model where
aging (ROS), inflammation (NFκB) … Citation20 Individually, each of these inflammatory cytokines …

… accelerated aging and death in SAM mice is their higher oxidative status [20, 21] compared
with normal mice. A relationship between cytokines and aging … anti-inflammatory cytokines IL-…