… ), is integrated by several transcription factors implicated in immune and inflammatory
responses [15], which are involved in the cellular senescence in embryonic fibroblasts, the TNF-α-…

… SASP activation, resulting in senescence. Our results demonstrate that the SASP can
cause paracrine senescence and impact on tumour suppression and senescence in vivo. …

… sustains a senescence-associated inflammatory response, we attempted to eliminate
senescent cells in Syrian hamsters by using senolytic drugs that can selectively kill senescent cells…

… or inappropriate activation of senescence contributes to tumour progression and malignancy.
This review will discuss the paracrine effects of senescent cells on different aspects of …

… by the senescent tumor cells and the senescent … senescence-associated inflammatory
responses in aging and cancer. We propose that controlling senescence-associated inflammation …

… Normally, the inflammatory response ceases within hours or days, once the foreign … of
senescent cells as a possible additional source. We describe the known effects of the senescence-…

… in senescent cells mimic the inflammatory response and wound repair process. The
inflammatory state of cellular senescence … by senescent cells also have paracrine functions. They …

… of the senescence-induced inflammatory responses in the context of cancer. A more complete
understanding of senescence … phenotype to neighboring cells via paracrine mechanisms …

… stem cells may regulate senescence features induced by inflammatory stress in OA …
down-regulated senescence markers induced by interleukin-1β including senescence-associated β-…

… -γ drive the antiviral response and senescence (8, 51). … inflammatory responses by BZLF1
during the EBV lytic life cycle is required to attenuate the transmission of paracrine senescence…