Integrative analysis of genomic and transcriptomic characteristics associated with progression of aggressive thyroid cancer

SK Yoo, YS Song, EK Lee, J Hwang, HH Kim… - Nature …, 2019 - nature.com
… The Cancer Genome Atlas (TCGA) proposed two molecular subtypes of papillary thyroid
cancer (PTC), BRAF V600E -like and RAS-like, based on transcriptome analysis 1 . Moreover, …

Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

CM Beltrami, MB Dos Reis, MC Barros-Filho… - Clinical …, 2017 - Springer
… The integrative analysis between gene expression and DNA … A similar integrative analysis
uncovered 40 of 254 differentially … Thyroid cancer is the most common tumor of the head and …

Integrative analysis of methylation and transcriptome identified epigenetically regulated lncRNAs with prognostic relevance for thyroid cancer

Q Li, P Wang, C Sun, C Wang, Y Sun - Frontiers in Bioengineering …, 2020 - frontiersin.org
… DNA methylation and lncRNA regulation in thyroid cancer (THCA) remain largely unknown.
In this study, we performed an integrated analysis of methylation and the transcriptome and …

Identification of Long Noncoding RNAs Deregulated in Papillary Thyroid Cancer and Correlated with BRAFV600E Mutation by Bioinformatics Integrative Analysis

L Goedert, JR Plaça, CS Fuziwara, MCR Machado… - Scientific Reports, 2017 - nature.com
Thyroid cancer is the endocrine malignancy 1 that, although stable until the 1990s, has … the
thyroid cancers originate from the follicular cell epithelium 1 , which includes papillary thyroid

Integrative analysis of potential biomarkers involved in the progression of papillary thyroid cancer

R Bansal, U Saxena - Applied biochemistry and biotechnology, 2023 - Springer
… Here, our aim is to analyze the differentially expressed genes (DEGs) which are consistently
upregulated in papillary thyroid cancer. For this study, we considered only those genes …

Characterizing dedifferentiation of thyroid cancer by integrated analysis

H Luo, X Xia, GD Kim, Y Liu, Z Xue, L Zhang, Y Shu… - Science …, 2021 - science.org
… This variation in cell proportion clustering was verified by deconvolution analysis using bulk
transcriptome profiles of thyroid cancer tissues (45 normal, 49 PTC, and 11 ATC samples) (…

Integrative analysis of DNA methylation and gene expression identified follicular thyroid cancer-specific diagnostic biomarkers

Y Yao, P Xu, T Ying, Y Wang, X Wang, L Shu… - Frontiers in …, 2022 - frontiersin.org
… In this study, we analyzed DNA methylation and gene expression profiles in follicular thyroid
cancer samples and benign thyroid lesion samples in our own cohort. One methylation site …

[HTML][HTML] A multimodal integrative approach to model transcriptional addiction of thyroid cancer on RUNX2

E Vitale, E Sauta, M Gugnoni, F Torricelli… - Cancer …, 2022 - ncbi.nlm.nih.gov
thyroid cancer, providing evidence of a role for this TF in mastering S‐ENH function in cancer
data, describes the transcriptional dependency of thyroid cancer on the genomic activity of …

Integrative multi-omics analysis reveals different metabolic phenotypes based on molecular characteristics in thyroid cancer

YH Kim, SJ Yoon, M Kim, HH Kim, YS Song… - Clinical Cancer …, 2024 - AACR
… Molecular subtypes and metabolic properties of thyroid cancer. A, Schematic diagram
depicting the molecular subtypes of thyroid cancer and our integrative multi-omics analysis

[HTML][HTML] A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors

Q Cheng, X Li, CR Acharya, T Hyslop, JA Sosa - Oncotarget, 2017 - ncbi.nlm.nih.gov
… is associated with the risk of cancer in a thyroid nodule [8, 9]. … , Asuragen miRInform™ thyroid
panel, and ThyroSeq offer … evaluation of thyroid nodules and the risk of thyroid cancer in the …