[HTML][HTML] Early life adversity and neuropsychiatric disease: differential outcomes and translational relevance of rodent models

RC Waters, E Gould - Frontiers in systems neuroscience, 2022 - frontiersin.org
… The study presented strong evidence that a high degree of childhood adversity increased …
childhood adversity and health outcomes whereby a greater number of adversities was …

Timing, duration, and differential susceptibility to early life adversities and cardiovascular disease risk across the lifespan: Implications for future research

SF Suglia, AA Appleton, ME Bleil, RA Campo… - Preventive …, 2021 - Elsevier
… When this and other potential factors that give rise to differential ELA exposure are more
thoroughly studied, we may better explain disparities in cardiometabolic health outcomes and, …

[HTML][HTML] The effect of cumulative early life adversities, and their differential mediation through hair cortisol levels, on childhood growth and cognition: Three-year follow …

D Mukherjee, S Bhopal, S Bhavnani… - Wellcome open …, 2022 - ncbi.nlm.nih.gov
… We aimed to estimate the associations between prospectively measured cumulative early
adversities with growth and cognition outcomes in rural Indian preschool children and to …

Association of childhood adversity with differential susceptibility of transdiagnostic psychopathology to environmental stress in adulthood

CS Albott, MK Forbes, JJ Anker - JAMA network open, 2018 - jamanetwork.com
… Notably, the differential susceptibility associations found in the … of differential susceptibility.
For example, our moderator (childhood adversity) is robustly associated with our outcome

[HTML][HTML] Sex-specific and strain-dependent effects of early life adversity on behavioral and epigenetic outcomes

M Kundakovic, S Lim, K Gudsnuk… - Frontiers in …, 2013 - frontiersin.org
… between early life adversity, genetic background, and sex in the determination of
neurobehavioral and epigenetic outcomes that may account for differential vulnerability to later-…

Early life adversity is associated with differential gene expression in immune cells: A cluster-based analysis across an acute psychosocial stressor

L Etzel, AT Apsley, WJ Hastings, Q Ye… - Brain, Behavior, and …, 2024 - Elsevier
… Elucidating mechanisms by which early-life adversity (ELA) contributes to increased disease
risk is important for mitigating adverse health outcomes. Prior work has found differences in …

[HTML][HTML] Differential susceptibility of the developing brain to contextual adversity and stress

WT Boyce - Neuropsychopharmacology, 2016 - nature.com
… of their social environments, sustaining unusually poor outcomes in environments of adversity
but exceptionally positive adaptive outcomes in supportive and nurturing social contexts. …

Early life adversity and adult biological risk profiles

EM Friedman, AS Karlamangla… - Psychosomatic …, 2015 - journals.lww.com
… the differential effects of several different types of adversitiesoutcome reflecting cumulative
adult biological risk profiles (rather than focusing on specific biological or disease outcomes) …

[HTML][HTML] Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?

AM Vaiserman, AK Koliada - Human genomics, 2017 - Springer
… suggests that adversities at critical periods in early life, both … , as well as neuropsychiatric
outcomes in later life. Currently, … early-life events and adult neurobehavioral outcomes. Role of …

Early adversity and adult health outcomes

SE Taylor, BM Way, TE Seeman - Development and …, 2011 - cambridge.org
Adversity in childhood has effects on mental and physical health, not only in childhood but
across the lifespan. A chief task of our research has been to define the pathways by which …