Early life adversity and neuropsychiatric disease: differential outcomes and translational relevance of rodent models

RC Waters, E Gould - Frontiers in systems neuroscience, 2022 - frontiersin.org
… between ELA and adult neuropsychiatric disease. While a comprehensive evaluation of
genetic and epigenetic variables mediating ELA-induced neuropsychiatric disease is far beyond …

Early-life adversity and neurological disease: age-old questions and novel answers

AK Short, TZ Baram - Nature Reviews Neurology, 2019 - nature.com
… on how early-life adversity could modulate cognitive functions … ,19,20,21,22 , and late-life
dementia 17,18,23 . The types of … are models of specific neuropsychiatric diseases; rather, they …

Early-life adversity, systemic inflammation and comorbid physical and psychiatric illnesses of adult life

MA Nettis, CM Pariante, V Mondelli - Neuroinflammation and …, 2020 - Springer
adversities can be considered as environmental insults happening in a critical developmental
phase of life… Supporting this hypothesis, childhood adversities are strongly associated with …

Early life adversity as a risk factor for cognitive impairment and Alzheimer's disease

Z Huang, JD Jordan, Q Zhang - Translational neurodegeneration, 2023 - Springer
… factors may contribute to the pathogenesis of these diseases. Early life adversity (ELA) has
a profound impact on brain function and health later in life. In rodent models, exposure to ELA …

Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?

AM Vaiserman, AK Koliada - Human genomics, 2017 - Springer
… , as well as neuropsychiatric outcomes in later life. Currently, the … how adversity early in life
can affect neurobehavioral development of animals and place them on a pathway to disease. …

The long-term impact of early adversity on late-life psychiatric disorders

A Gershon, K Sudheimer, R Tirouvanziam… - Current psychiatry …, 2013 - Springer
… The findings of this review highlight that exposure to adversity early in life is capable of
exerting long-term risk for a range of neuropsychiatric outcomes. Such findings underscore the …

The long-term impact of early adversities on psychiatric disorders: focus on neuronal plasticity

A Luoni, J Richetto, G Racagni… - Current Pharmaceutical …, 2015 - ingentaconnect.com
… comprehensive review of the role of early life adversities in the origins of psychiatric disorders …
of vitamin D and neuropsychiatric disease. Frontiers Neuroendocrinol 2013; 34(1): 47-64. …

Effects of early-life adversities on neuropsychiatric and executive functions in HIV-positive adults

US Clark, OD Herrington, RR Hegde - Journal of the International …, 2023 - cambridge.org
… Our results thus illuminate the ways in which different types of early-life adversity elevate
the risk of neuropsychiatric and neurocognitive symptoms in HIV+ samples. To our knowledge, …

Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease

JA Hollander, DA Cory-Slechta, FN Jacka… - …, 2020 - nature.com
… early-life adversity), to the pathogenesis of neuropsychiatric abnormalities have been well-studied
(and discussed elsewhere) [4,5,6,7] compared to non-pharmaceutical chemicals that …

Impact of childhood adversity, as early life distress, on cytokine alterations in schizophrenia

C Miljevic, A Munjiza-Jovanovic… - Neuropsychiatric …, 2023 - Taylor & Francis
Even though inflammation theory has been introduced in the pathophysiology of psychosis
almost a century ago, many of its aspects have remained unelucidated. Numerous studies …