Genes and longevity of lifespan

MN Bin-Jumah, MS Nadeem, SJ Gilani… - International Journal of …, 2022 - mdpi.com
… exhibits high heritability, insights into the genetic factors may improve our present …
review of human genes and their non-human orthologs associated with the life expectancy. …

Genetics of longevity and aging

J Vijg, Y Suh - Annu. Rev. Med., 2005 - annualreviews.org
… Unlike life expectancy (mean age at death), maximum life … for the kind of genes that specify
longevity and aging in different … in identifying candidate longevity and aging genes in model …

Genetic contribution to aging: deleterious and helpful genes define life expectancy

JI Lao, C Montoriol, I Morer… - Annals of the New York …, 2005 - Wiley Online Library
… of genes that alter longevity by modulating the risk of early-life pathology and disease.19 …
groups: genes that promote longevity (helpful alleles) and genes that decrease length of life (…

Genetic influence on human lifespan and longevity

JB Hjelmborg, I Iachine, A Skytthe, JW Vaupel… - Human genetics, 2006 - Springer
… of genetic influence on longevity, as for BMI. We remark that one may consider ‘years of life
… The first is based on studying the life expectancy of MZ and DZ twins while conditioning on …

How important are genes to achieve longevity?

C Caruso, ME Ligotti, G Accardi, A Aiello… - International Journal of …, 2022 - mdpi.com
… The increase in life expectancy with the consequent aging of the population is a great
achievement of humanity, but it also represents a challenge that the Western world is currently …

Healthy lifestyle in late-life, longevity genes, and life expectancy among older adults: a 20-year, population-based, prospective cohort study

J Wang, C Chen, J Zhou, L Ye, Y Li, L Xu… - … Healthy longevity, 2023 - thelancet.com
… Lifestyle and longevity genes have different and important … in late-life and life expectancy
mediated by genetic risk is yet to … -life and genetic risk with life expectancy among older adults. …

Genetic factors associated with longevity: a review of recent findings

AH Shadyab, AZ LaCroix - Ageing research reviews, 2015 - Elsevier
Life expectancy and the rate of survival into old age have risen dramatically throughout the
past century in the United States. Between 2000 and 2010, the population aged ≥65 years …

Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study

J Stessman, Y Maaravi… - Mechanisms of ageing …, 2005 - Elsevier
… Moreover, the role of specific genes in contributing to human longevity is only now slowly …
as a useful roadmap towards unraveling the complex genetic architecture of human longevity. …

Unlocking the secrets of longevity genes

DA Sinclair, L Guarente - Scientific American, 2006 - JSTOR
TAPPING THE POWER of longevity genes could change the arc of a typical human lifetime:
instead of vitality and growth giving way to the decline of old age, a person might be able to …

Longevity and aging: role of genes and of the extracellular matrix

L Robert, J Labat-Robert - Biogerontology, 2015 - Springer
… As every animal species has a different genome and also a specific life expectancy, a “logical”
prediction could have been that “life expectancy” is “coded in the genome”. However, as …