… drop intervals of the linkage analysis as candidate genes for longevity, we have … analysis
(Table S3, Data S4). The 1-LOD drop intervals were investigated for association with longevity …

… To map the loci conferring a survival advantage, we performed the second genomewide
linkage scan on human longevity and the first using a high-density marker panel of single …

… are enabling us to conduct genome-wide association and linkage analyses in search of
genes that modulate human ageing and longevity. Meanwhile, with the fast growing functional …

… In this respect, we are combining the molecular epidemiological studies in human longevity
with cell biological approaches (figure 2). Especially when performing such analyses in the …

… (GWAS) of parental longevity in European descent UK Biobank … The results suggest that
human longevity is highly polygenic … There may also be gender specific routes to longevity. …

… of linkage analysis to identify deleterious variants, whereas efficiency for identification of
longevity … In this paper, we derived models for longevity and for the part on linkage analysis we …

… non-parametric linkage analysis of affected sib-pairs (ASP) [Kruglyak and Lander, 1995:
Am J Hum Genet 57:439–454] to localize genes that contribute to human longevity using long…

… To investigate further the potential links of HGPS, LMNA, and progerin … human longevity.
Toward this end, we tested variants of the LMNA gene for association with extreme longevity in …

… Therefore, multipoint genome-wide affected-only parametric linkage analyses were conducted
by using the allegro program under both a dominant and recessive model with reduced …

… Similarly, we previously performed a pathway analysis of … of this pathway in human longevity
(Debrabant et al., 2014). … to three main candidate pathways of human longevity such as IIS, …