Genes of human longevity: an endless quest?

M Capri, A Santoro, P Garagnani… - Current vascular …, 2014 - ingentaconnect.com
… for longevity. Further, we will summarise the role of apolipoprotein E (APOE) variants in human
longevity … Genome-wide linkage analysis for human longevity: Genetics of healthy ageing …

Spatial analysis and surname analysis: complementary tools for shedding light on human longevity patterns

A Montesanto, G Passarino, A Senatore… - Annals of human …, 2008 - Wiley Online Library
… Starting from the observation that human longevity patterns show regional variations, we
applied Spatial Analysis (using the Geographic Information System) and Surname …

Causes, effects, and constraints in the genetics of human longevity

F Schächter - The American Journal of Human Genetics, 1998 - cell.com
… year, being the oldest human being alive on earth, epitomized our quest for longevity. This
deeply … Calment's ancestry revealed a striking aggregation of the longevity trait: 24% of her 55 …

[HTML][HTML] Phenome and genome based studies into human ageing and longevity: An overview

PE Slagboom, N van den Berg, J Deelen - Biochimica Et Biophysica Acta …, 2018 - Elsevier
… the most prominent key to longevity seemed to be the … human longevity has not been
revealed to such extend, however. We will now discuss the genetic component in human longevity

Power assessment for genetic association study of human longevity using offspring of long-lived subjects

Q Tan, JH Zhao, S Li, TA Kruse… - European journal of …, 2010 - Springer
… As a complex trait, human longevity involves a large number of … analysis in fine mapping
genes that contribute to human complex traits. In longevity studies, genetic association analysis

Genetics of healthy aging and longevity

AR Brooks-Wilson - Human genetics, 2013 - Springer
… Larger sample sets and denser and more informative linkage analyses were pointing away
from the original chromosome 4 linkage observation, and converging instead most strongly …

Genetics of human longevity from incomplete data: new findings from the long life family study

AI Yashin, KG Arbeev, D Wu, LS Arbeeva… - The Journals of …, 2018 - academic.oup.com
… , we also detected a strong new association with longevity of … relevance of the detected SNPs
to human longevity. … , were used in our genetic analyses of human longevity. For simplicity, …

Investigation of genetic susceptibility factors for human longevity–a targeted nonsynonymous SNP study

F Flachsbart, A Franke, R Kleindorp, A Caliebe… - Mutation Research …, 2010 - Elsevier
… and rs648802 influence human longevity, analyses in a … EXO1 as modifiers of human longevity
it was demonstrated for … repair, respectively) can be translated to human ageing [18], [19], […

Inheritance of human longevity in Iceland

H Gudmundsson, DF Gudbjartsson, A Kong… - … Journal of Human …, 2000 - nature.com
… The idea that human longevity is influenced by genetic … have confirmed that human longevity
is moderately inherited. … is a significant genetic component to longevity. In addition, age-…

Common variants in SIRT1 and human longevity in a Chinese population

R Lin, D Yan, Y Zhang, X Liao, G Gong, J Hu, Y Fu… - BMC Medical …, 2016 - Springer
… of SIRT1 gene in human longevity. Therefore, in this study, we attempted to analyze the
association between common variations in the SIRT1 gene and human longevity in a Chinese …