Plasma testosterone levels in C57BL/6J male mice: effects of age and disease

JF Nelson, KR Latham, CE Finch - European Journal of …, 1975 - academic.oup.com
… , of testosterone is unaltered in these mice during aging cannot be determined from this
study. Nevertheless these findings indicate that in aging male mice, as in male humans, plasma …

Male determined accelerated autoimmune disease in BXSB mice: transfer by bone marrow and spleen cells.

RA Eisenberg, S Izui, PJ McConahey… - … (Baltimore, Md.: 1950 …, 1980 - journals.aai.org
… Our results indicate that the male-specific effect that produces accelerated disease in the …
-old mice, as well as spleens of 3- to 4-month-old mice. Moreover, the disease developed at the …

Voluntary wheel running differentially affects disease outcomes in male and female mice with experimental autoimmune encephalomyelitis

KA Mifflin, E Frieser, C Benson, G Baker… - Journal of …, 2017 - Elsevier
… However, these initial studies were carried out exclusively in female mice. The present …
on several disease parameters in male and female mice with EAE. Male and female mice were …

Sex-based differences in susceptibility to respiratory and systemic pneumococcal disease in mice

A Kadioglu, AM Cuppone, C Trappetti… - … infectious diseases, 2011 - academic.oup.com
… investigated in male and female mice in models of invasive pneumonia and sepsis. Male
mice were … in postpubertal male mice but not female mice [28]. In contrast, postpubertal female …

Middle-age male mice have increased severity of experimental autoimmune encephalomyelitis and are unresponsive to testosterone therapy

A Matejuk, C Hopke, AA Vandenbark… - The Journal of …, 2005 - journals.aai.org
… Testosterone levels are thought to decline naturally in aging men and animals, and this may
change the male response to disease. However, our results were apparently not affected by …

[HTML][HTML] Differential susceptibility to obesity between male, female and ovariectomized female mice

J Hong, RE Stubbins, RR Smith, AE Harvey, NP Núñez - Nutrition journal, 2009 - Springer
… that male mice are more likely to become obese than female mice and that the protection
against obesity in female mice is … with body weight such as cancer and cardiovascular disease. …

Hyperprolactinemia in male NZB/NZW (B/W) F1 mice: accelerated autoimmune disease with normal circulating testosterone

R McMurray, D Keisler, S Izui, SE Walker - Clinical immunology and …, 1994 - Elsevier
… In the current study, serum prolactin was elevated in male BW mice by pituitary transplantation,
a documented method of creating prolonged hyperprolactinemia (14). Grafted syngeneic …

[HTML][HTML] Diet-induced obesity in male C57BL/6 mice decreases fertility as a consequence of disrupted blood-testis barrier

Y Fan, Y Liu, K Xue, G Gu, W Fan, Y Xu, Z Ding - PloS one, 2015 - journals.plos.org
… a variety of diseases, such as cardiovascular disease, type II … well recognized, its harmfulness
to male fertility is still unclear … diet-induced obesity impairs male fertility and furthermore to …

Hepatocellular carcinoma associated with liver-gender disruption in male mice

AB Rogers, EJ Theve, Y Feng, RC Fry, K Taghizadeh… - Cancer research, 2007 - AACR
mice with severe, but not mild, diseasemale mice with chronic hepatitis is maturationally
imprinted and androgen-independent. Proinflammatory cytokines may promote HCC in a male-…

Sex hormone modulation of autoimmunity in NZB/NZW mice

J Roubinian, N Talal, PK Siiteri… - Arthritis & Rheumatism …, 1979 - Wiley Online Library
… prepubertal castration of male B/W mice caused premature … and given to female mice with
more advanced disease. DHT given … disease in B/W mice and may have therapeutic potential. …