… and because of the sheer complexity of mouse development. Here, we set out to systematically
reconstruct the major cellular trajectories of mammalian embryogenesis from E3.5 to E13.…

… the development of the mouse embryo from dozens of cells of … studies has yet to be
systematically integrated in a manner … as because of the sheer complexity of mouse development. …

… The mouse embryo has long been central to the study of … technologies capable of systematically
following cellular … the embryo implants into the uterus) the mouse embryo develops from …

… (3D) spatial transcriptomic profiling leverages mouse embryos from gastrulation (E5.5) to …
of mouse embryos at E9.5 and E11.5, with a widely applicable reconstruction workflow that …

… that underlies mouse embryogenesis through gastrulation, … reconstruction by summing the
log-likelihoods for all indels that appear in the tree, using likelihoods estimated from embryo …

… We require a representative embryo, and therefore do not attempt to reconstruct the embryo
as embedded, but allow some of the systematic (common to all sections) distortion to remain…

… The digital 2D sections obtained from full 3D reconstructed … of the mouse embryo from The
Atlas of Mouse Development … tool for systematic studies of the murine early embryogenesis …

… of subpopulations of cells in the developing embryo. Imaging is typically performed either …
of the embryogenesis of Caenorhabditis elegans, including the automated reconstruction of …

… Single-cell RNA-sequencing (RNA-seq) analysis has the potential to reconstruct the …
To systematically investigate the knockout phenotype of regulon transcription factors, we …

… For example, Klf5 is expressed ubiquitously in the preimplantation mouse embryo [70] and
is not only required for the normal transcription of Oct4, Sox2 and Nanog in the ICM, but also …