Plasma cell-free DNA methylation: a liquid biomarker of hepatic fibrosis

B Yiğit, M Boyle, O Özler, N Erden, F Tutucu, T Hardy… - Gut, 2018 - gut.bmj.com
DNA methylation markers at the human PPARγ promoter detectable in circulating cell-free
DNA (ccfDNA) that display differential methylation … , providing a biomarker of the underlying …

Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease

T Hardy, M Zeybel, CP Day, C Dipper, S Masson… - Gut, 2017 - gut.bmj.com
… to assess whether DNA methylation of circulating DNA could be detected in human plasma
and … Plasma cell-free circulating DNA methylation of PPARγ was quantitatively assessed by …

Crosstalk between DNA methylation and gene expression in colorectal cancer, a potential plasma biomarker for tracing this tumor

MA Kerachian, A Javadmanesh, M Azghandi… - Scientific reports, 2020 - nature.com
plasma. Since the main purpose of this study was to find new biomarkers for CRC detection,
a plasma … to demonstrate the eligibility of the candidate gene as a biomarker in plasma. This …

[HTML][HTML] SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma

C Kneip, B Schmidt, A Seegebarth… - Journal of Thoracic …, 2011 - Elsevier
… Stage and histology-specific performance of the SHOX2 DNA methylation biomarker using
plasma samples from patients with suspected lung cancer. In total, 371 plasma samples (169 …

Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers

J Clement, Q Yan, M Agrawal, RE Coronado… - Aging …, 2022 - Wiley Online Library
… We included six different DNA methylation-based aging biomarkers or epigenetic clocks
in this study. This included DNAmGrimAge (Lu, Quach, et al., 2019) and DNAmPhenoAge (…

Genome‐wide plasma cell‐free DNA methylation profiling identifies potential biomarkers for lung cancer

W Xu, J Lu, Q Zhao, J Wu, J Sun, B Han… - Disease …, 2019 - Wiley Online Library
… in intergenic regions, suggesting that DNA methylation may regulate gene expression in a …
patient plasma, we examined the methylation status of this set of genes with DNA methylation

DNA methylation biomarkers: cancer and beyond

T Mikeska, JM Craig - Genes, 2014 - mdpi.com
… for the discovery of DNA methylation biomarkers including cell-… tumor material and cell-free
DNA samples such as plasma. … biomarkers, in particular DNA methylation biomarkers, are …

Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients

L de Vos, H Gevensleben, A Schröck, A Franzen… - Clinical …, 2017 - Springer
… of SHOX2 as a biomarker has been confirmed in bronchial aspirates and plasma [11,12,13,…
sensitive and specific biomarker for the detection of colorectal cancer in plasma and has …

Methylated tumor-specific DNA as a plasma biomarker in patients with glioma

KD Weaver, SA Grossman, JG Herman - Cancer investigation, 2006 - Taylor & Francis
DNA was extracted from both plasma and tumor specimens using proteinase K digestion [Citation[24]].
DNA methylation patterns in the CpG island of target gene promoters was …

[HTML][HTML] DNA methylation GrimAge strongly predicts lifespan and healthspan

AT Lu, A Quach, JG Wilson, AP Reiner, A Aviv… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
… Our DNAm-based surrogate biomarkers of plasma protein levels may be leveraged by …
DNA methylation data Our study involved DNA methylation data generated on two different …