An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
… be effective against SARS-CoV-2, the etiological agent of COVID-19. Hydroxychloroquine, …
syndrome coronavirus 2 (SARS-CoV-2), causes the Coronavirus Disease 2019 (COVID-19), …

[HTML][HTML] Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

C Wu, Y Liu, Y Yang, P Zhang, W Zhong… - … Pharmaceutica Sinica B, 2020 - Elsevier
SARS-CoV-2 and SARS-CoV, the structure and function prediction of SARS-CoV-2
genome … protein were mainly based on those researches on homology protein in SARS-CoV. …

Anti-SARS-CoV-2 potential of artemisinins in vitro

R Cao, H Hu, Y Li, X Wang, M Xu, J Liu… - ACS Infectious …, 2020 - ACS Publications
… (14) In this study, we systematically evaluated the antiviral potential of artemisinins against
SARS-CoV-2 in vitro and discovered that artesunate could inhibit SARS-CoV-2 replication in …

FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
… In December 2019, a novel SARS-CoV-2 coronavirus … all been successful in inhibiting
SARS-CoV-2 in vitro. The initial … The results of clinical trials point to the potential clinical efficacy …

The neuroinvasive potential of SARSCoV2 may play a role in the respiratory failure of COVID19 patients

YC Li, WZ Bai, T Hashikawa - Journal of medical virology, 2020 - Wiley Online Library
… between SARS-CoV and SARS-CoV2, it remains to know whether the potential neuroinvasion
of SARS-CoV-2 plays a role in the acute respiratory failure of patients with COVID-19. …

[HTML][HTML] Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

Y Huang, C Yang, X Xu, W Xu, S Liu - Acta Pharmacologica Sinica, 2020 - nature.com
… was quickly discovered to be caused by a coronavirus later named severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) [1], which belongs to the β coronavirus family. It is …

[HTML][HTML] Potential presymptomatic transmission of SARS-CoV-2, Zhejiang province, China, 2020

ZD Tong, A Tang, KF Li, P Li, HL Wang… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
2 persons with confirmed cases of symptomatic COVID-19 after their exposure to a potentially
presymptomatic person who was later diagnosed with laboratory-confirmed COVID-19. …

Anti-SARS-CoV natural products with the potential to inhibit SARS-CoV-2 (COVID-19)

S Verma, D Twilley, T Esmear… - Frontiers in …, 2020 - frontiersin.org
… ), known to cause the disease COVID-19, was declared a … potential of plants and natural
products to inhibit coronavirus … , which may have potential activity against SARS-CoV-2. Due to …

Understanding SARS-CoV-2-mediated inflammatory responses: from mechanisms to potential therapeutic tools

Y Fu, Y Cheng, Y Wu - Virologica Sinica, 2020 - Springer
SARS-CoV-2 infection remain largely unknown. In this review, we attempt to discuss and
summarize possible mechanisms of SARS-CoV-2-… cause of fatality in SARS-CoV-2 infection, we …

Emerging SARS-CoV-2 variants of concern and potential intervention approaches

J Khateeb, Y Li, H Zhang - Critical Care, 2021 - Springer
coronavirus 2 (SARS-CoV-2) variants of concern (VOC) poses a major threat on international
public health as the rapid change of the SARS-CoV-2 … clinical management [1, 2]. Yet, it is …