Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.
M Hibi, A Lin, T Smeal, A Minden… - Genes & …, 1993 - genesdev.cshlp.org
The activity of c-Jun is regulated by phosphorylation. Various stimuli including transforming
oncogenes and UV light, induce phosphorylation of serines 63 and 73 in the amino-terminal …
oncogenes and UV light, induce phosphorylation of serines 63 and 73 in the amino-terminal …
Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor.
M Granger-Schnarr, E Benusiglio… - Proceedings of the …, 1992 - National Acad Sciences
Transcription factor c-Jun appears to be a nuclear target of the Ras-induced signal
transduction pathway. In fact, some experiments show that transforming forms of the Ras …
transduction pathway. In fact, some experiments show that transforming forms of the Ras …
Structure and chromosomal localization of the functional intronless human JUN protooncogene.
K Hattori, P Angel, MM Le Beau… - Proceedings of the …, 1988 - National Acad Sciences
The JUN protooncogene encodes a protein that is functionally and biochemically identical to
the transcription factor AP-1 (activator protein 1). To understand the structure and regulation …
the transcription factor AP-1 (activator protein 1). To understand the structure and regulation …
Identification of NF‐jun, a novel inducible transcription factor that regulates c‐jun gene transcription.
MA Brach, F Herrmann, H Yamada, PA Bäuerle… - The EMBO …, 1992 - embopress.org
In this study we report the identification of a novel transcription factor, termed Nuclear Factor‐
jun (NF‐jun). This factor contributes to inducible transcription of the c‐jun gene in human …
jun (NF‐jun). This factor contributes to inducible transcription of the c‐jun gene in human …
[HTML][HTML] Transcriptional activation of yeast nucleotide biosynthetic gene ADE4 by GCN4.
HU Mösch, B Scheier, R Lahti, P Mäntsäla… - Journal of Biological …, 1991 - Elsevier
The yeast transcriptional regulator protein GCN4 harbors the bZIP DNA binding motif, which
is common to a family of DNA-binding proteins in eukaryotic organisms from yeast to man …
is common to a family of DNA-binding proteins in eukaryotic organisms from yeast to man …
nit-4, a pathway-specific regulatory gene of Neurospora crassa, encodes a protein with a putative binuclear zinc DNA-binding domain
GF Yuan, YH Fu, GA Marzluf - Molecular and cellular biology, 1991 - Am Soc Microbiol
Abstract nit-4, a pathway-specific regulatory gene in the nitrogen circuit of Neurospora
crassa, is required for the expression of nit-3 and nit-6, the structural genes which encode …
crassa, is required for the expression of nit-3 and nit-6, the structural genes which encode …
Mutation of a phosphorylation site in the DNA-binding domain is required for redox-independent transactivation of AP1-dependent genes by v-Jun.
T Oehler, A Pintzas, S Stumm, A Darling, D Gillespie… - Oncogene, 1993 - europepmc.org
The ability of the nuclear oncoprotein Jun to activate transcription is controlled both by level
of DNA binding and by the activity of its transactivation domain. Control of DNA binding is …
of DNA binding and by the activity of its transactivation domain. Control of DNA binding is …
JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.
T Kallunki, B Su, I Tsigelny, HK Sluss… - Genes & …, 1994 - genesdev.cshlp.org
The transcriptional activity of c-Jun is augmented through phosphorylation at two sites by a c-
Jun amino-terminal kinase (JNK). All cells express two distinct JNK activities, 46 and 55 kD …
Jun amino-terminal kinase (JNK). All cells express two distinct JNK activities, 46 and 55 kD …
Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.
PM Chevray, D Nathans - Proceedings of the National …, 1992 - National Acad Sciences
To identify proteins that interact with Jun or Fos we have used the protein interaction cloning
system developed by S. Fields and O.-K. Song [(1989) Nature (London) 340, 245-246] to …
system developed by S. Fields and O.-K. Song [(1989) Nature (London) 340, 245-246] to …
The avian cellular homolog of the oncogene jun.
T Nishimura, PK Vogt - Oncogene, 1988 - europepmc.org
We have isolated chicken genomic and cDNA clones representing the jun oncogene of
avian sarcoma virus 17 (ASV17). The genomic clone lacks intron sequences within its …
avian sarcoma virus 17 (ASV17). The genomic clone lacks intron sequences within its …