Recently, three landmark cross-tissue single-cell atlases were published in Science, by the
Tabula Sapiens Consortium, 1 Eraslan et al., 2 and Domínguez Conde et al., 3 respectively …

To the Editor—Building the Human Cell Atlas (HCA) requires consistent and agile
experimental designs, standardized operating protocols (SOPs), benchmarks and quality …

The cell is the fundamental constituent unit of a mammal which, in turn, depends on the
cooperative work of various cells to compose intricate life activities. Cells harbor diverse …

The development of single-cell and spatial transcriptomics methods was instrumental in the
conception of the Human Cell Atlas initiative, which aims to generate an integrated map of …

Our understanding of how cells form distinct tissues and organs and interact with each other
is limited. Recent single-cell RNA sequencing (scRNA-seq) analyses have described the …

Single-cell atlases promise to provide a 'missing link'between genes, diseases and
therapies. By identifying the specific cell types, states, programs and contexts where disease …

The Human Cell Atlas (HCA) will be made up of comprehensive reference maps of all
human cells-the fundamental units of life-as a basis for understanding fundamental human …

Cell atlases are essential companions to the genome as they elucidate how genes are used
in a cell type–specific manner or how the usage of genes changes over the lifetime of an …

Single-cell RNA-sequencing (scRNA-seq) is being used extensively to measure the mRNA
expression of individual cells from deconstructed tissues, organs and even entire organisms …

Comprehensively characterizing the cellular composition and organization of tissues has
been a long-term scientific challenge that has limited our ability to study fundamental and …