Identification of novel prognostic targets in glioblastoma using bioinformatics analysis
X Yin, Q Wu, Z Hao, L Chen - Biomedical engineering online, 2022 - Springer
Background Glioblastoma (GBM) is the most malignant grade of glioma. Highly aggressive
characteristics of GBM and poor prognosis cause GBM-related deaths. The potential …
characteristics of GBM and poor prognosis cause GBM-related deaths. The potential …
Characterization of the genomic and immunologic diversity of malignant brain tumors through multisector analysis
MO Schaettler, MM Richters, AZ Wang, ZL Skidmore… - Cancer discovery, 2022 - AACR
Despite some success in secondary brain metastases, targeted or immune-based therapies
have shown limited efficacy against primary brain malignancies such as glioblastoma …
have shown limited efficacy against primary brain malignancies such as glioblastoma …
Development and validation of a tumor mutation burden–related immune prognostic model for lower-grade glioma
W Yin, X Jiang, J Tan, Z Xin, Q Zhou, C Zhan… - Frontiers in …, 2020 - frontiersin.org
Tumor mutation burden (TMB) is a useful biomarker to predict prognosis and the efficacy of
immune checkpoint inhibitors (ICIs). In this study, we aimed to explore the prognostic value …
immune checkpoint inhibitors (ICIs). In this study, we aimed to explore the prognostic value …
A novel prognostic signature of transcription factors for the prediction in patients with GBM
Q Cheng, C Huang, H Cao, J Lin, X Gong, J Li… - Frontiers in …, 2019 - frontiersin.org
Background: Although the diagnosis and treatment of glioblastoma (GBM) is significantly
improved with recent progresses, there is still a large heterogeneity in therapeutic effects …
improved with recent progresses, there is still a large heterogeneity in therapeutic effects …
[HTML][HTML] Mining TCGA database for genes of prognostic value in glioblastoma microenvironment
Glioblastoma (GBM) is one of the most deadly brain tumors. The convenient access to The
Cancer Genome Atlas (TCGA) database allows for large-scale global gene expression …
Cancer Genome Atlas (TCGA) database allows for large-scale global gene expression …
Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression
Glioblastoma (GBM) is a common malignant brain tumor which often presents as a
comorbidity with central nervous system (CNS) disorders. Both CNS disorders and GBM …
comorbidity with central nervous system (CNS) disorders. Both CNS disorders and GBM …
Elevated TYROBP expression predicts poor prognosis and high tumor immune infiltration in patients with low-grade glioma
J Lu, Y Peng, R Huang, Z Feng, Y Fan, H Wang, Z Zeng… - BMC cancer, 2021 - Springer
Background Tyrosine protein tyrosine kinase binding protein (TYROBP) binds non-
covalently to activated receptors on the surface of various immune cells, and mediates …
covalently to activated receptors on the surface of various immune cells, and mediates …
Recurrence-and malignant progression-associated biomarkers in low-grade gliomas and their roles in immunotherapy
C Teng, Y Zhu, Y Li, L Dai, Z Pan, S Wanggou… - Frontiers in …, 2022 - frontiersin.org
Despite a generally better prognosis than high-grade glioma (HGG), recurrence and
malignant progression are the main causes for the poor prognosis and difficulties in the …
malignant progression are the main causes for the poor prognosis and difficulties in the …